Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient childr...

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Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, Jeppe T, Jarrett, Ruth F, Koch, Anders, Garred, Peter, Freeland, June M L, Andersen, Andreas, Melbye, Mads
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Greenland
Online Access:https://curis.ku.dk/portal/da/publications/mannosebinding-lectin-genotypes-and-susceptibility-to-epsteinbarr-virus-infection-in-infancy(516f4169-0162-4fa8-8236-0c77c81701cd).html
https://doi.org/10.1128/CVI.00527-09
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spelling ftcopenhagenunip:oai:pure.atira.dk:publications/516f4169-0162-4fa8-8236-0c77c81701cd 2024-04-14T08:12:21+00:00 Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy Friborg, Jeppe T Jarrett, Ruth F Koch, Anders Garred, Peter Freeland, June M L Andersen, Andreas Melbye, Mads 2010-09-01 https://curis.ku.dk/portal/da/publications/mannosebinding-lectin-genotypes-and-susceptibility-to-epsteinbarr-virus-infection-in-infancy(516f4169-0162-4fa8-8236-0c77c81701cd).html https://doi.org/10.1128/CVI.00527-09 eng eng info:eu-repo/semantics/restrictedAccess Friborg , J T , Jarrett , R F , Koch , A , Garred , P , Freeland , J M L , Andersen , A & Melbye , M 2010 , ' Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy ' , Clinical and Vaccine Immunology (Online) , vol. 17 , no. 9 , pp. 1484-7 . https://doi.org/10.1128/CVI.00527-09 article 2010 ftcopenhagenunip https://doi.org/10.1128/CVI.00527-09 2024-03-21T17:28:07Z In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy. Article in Journal/Newspaper Greenland University of Copenhagen: Research Greenland Clinical and Vaccine Immunology 17 9 1484 1487
institution Open Polar
collection University of Copenhagen: Research
op_collection_id ftcopenhagenunip
language English
description In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.
format Article in Journal/Newspaper
author Friborg, Jeppe T
Jarrett, Ruth F
Koch, Anders
Garred, Peter
Freeland, June M L
Andersen, Andreas
Melbye, Mads
spellingShingle Friborg, Jeppe T
Jarrett, Ruth F
Koch, Anders
Garred, Peter
Freeland, June M L
Andersen, Andreas
Melbye, Mads
Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
author_facet Friborg, Jeppe T
Jarrett, Ruth F
Koch, Anders
Garred, Peter
Freeland, June M L
Andersen, Andreas
Melbye, Mads
author_sort Friborg, Jeppe T
title Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
title_short Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
title_full Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
title_fullStr Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
title_full_unstemmed Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
title_sort mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy
publishDate 2010
url https://curis.ku.dk/portal/da/publications/mannosebinding-lectin-genotypes-and-susceptibility-to-epsteinbarr-virus-infection-in-infancy(516f4169-0162-4fa8-8236-0c77c81701cd).html
https://doi.org/10.1128/CVI.00527-09
geographic Greenland
geographic_facet Greenland
genre Greenland
genre_facet Greenland
op_source Friborg , J T , Jarrett , R F , Koch , A , Garred , P , Freeland , J M L , Andersen , A & Melbye , M 2010 , ' Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy ' , Clinical and Vaccine Immunology (Online) , vol. 17 , no. 9 , pp. 1484-7 . https://doi.org/10.1128/CVI.00527-09
op_rights info:eu-repo/semantics/restrictedAccess
op_doi https://doi.org/10.1128/CVI.00527-09
container_title Clinical and Vaccine Immunology
container_volume 17
container_issue 9
container_start_page 1484
op_container_end_page 1487
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