Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient childr...

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Bibliographic Details
Published in:Clinical and Vaccine Immunology
Main Authors: Friborg, Jeppe T, Jarrett, Ruth F, Koch, Anders, Garred, Peter, Freeland, June M L, Andersen, Andreas, Melbye, Mads
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Greenland
Online Access:https://curis.ku.dk/portal/da/publications/mannosebinding-lectin-genotypes-and-susceptibility-to-epsteinbarr-virus-infection-in-infancy(516f4169-0162-4fa8-8236-0c77c81701cd).html
https://doi.org/10.1128/CVI.00527-09
Description
Summary:In a cohort study of children <4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

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