Enzymatic kinetic resolution of racemic ibuprofen: past, present and future

• Published in: Critical Reviews in Biotechnology
• Main Authors: José, Carla, Toledo, Victoria, Briand, Laura Estefania
• Format: Article in Journal/Newspaper
• Language: English
• Published: Taylor & Francis
• Subjects: Enantiomeric Esterification; Ibuprofen; Kinetic Resolution; Lipases; https://purl.org/becyt/ford/2.9; https://purl.org/becyt/ford/2; Argentina; Briand; Rugosa; Toledo; Antarc*; Antarctica
• Online Access: http://hdl.handle.net/11336/41825

This review is a journey concerning the investigations of the kinetic resolution of racemic ibuprofen for the last 20 years. The relevancy of the pharmacological uses of the S( + ) enantiomer along with its higher cost compared with racemic profen are the driving forces of a variety of scientific re...