nance of polyploid cell growth in breast cancer cells. Of 5760 human genes screened, 177 were found to induce severe DNA content alterations on prolonged transient silencing. Association with response to DNA damage stim-ulus and DNA repair was found to be the most enriche ional validation analysis o...

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Other Authors: The Pennsylvania State University CiteSeerX Archives
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Language:English
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Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS21
2 Hans Kristian Moen Vollan‡
§
Anna-Riina Aaltola
Petra Laasola
Sami Kilpinen†
Pet
Aaltola
Moen
Vollan
sami
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.252
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf
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spelling ftciteseerx:oai:CiteSeerX.psu:10.1.1.688.252 2023-05-15T18:11:53+02:00 The Pennsylvania State University CiteSeerX Archives application/pdf http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.252 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf en eng http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.252 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf Metadata may be used without restrictions as long as the oai identifier remains attached to it. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS21 2 Hans Kristian Moen Vollan‡ § ¶ Anna-Riina Aaltola Petra Laasola Sami Kilpinen† Pet text ftciteseerx 2016-01-08T18:13:47Z nance of polyploid cell growth in breast cancer cells. Of 5760 human genes screened, 177 were found to induce severe DNA content alterations on prolonged transient silencing. Association with response to DNA damage stim-ulus and DNA repair was found to be the most enriche ional validation analysis of these genes highlighted GINS2 a ccu-mulation of endogenous DNA damage, and impairing and induction of polyploidy by suppression of GINS2 was atic analysis of published gene expression and DNA copy NS2 to be associated with the aggressive characteristics o lear GINS2 protein levels distinguished actively proliferating g as tial t Abbreviati qRT- ll spot microarray Text sami Unknown Aaltola ENVELOPE(27.383,27.383,69.250,69.250) Moen ENVELOPE(14.664,14.664,66.828,66.828) Vollan ENVELOPE(13.556,13.556,66.742,66.742)
institution Open Polar
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op_collection_id ftciteseerx
language English
topic Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS21
2 Hans Kristian Moen Vollan‡
§

Anna-Riina Aaltola
Petra Laasola
Sami Kilpinen†
Pet
spellingShingle Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS21
2 Hans Kristian Moen Vollan‡
§

Anna-Riina Aaltola
Petra Laasola
Sami Kilpinen†
Pet
topic_facet Phenotypes in Breast Cancer Cells Identifies an Oncogenic Profile for GINS21
2 Hans Kristian Moen Vollan‡
§

Anna-Riina Aaltola
Petra Laasola
Sami Kilpinen†
Pet
description nance of polyploid cell growth in breast cancer cells. Of 5760 human genes screened, 177 were found to induce severe DNA content alterations on prolonged transient silencing. Association with response to DNA damage stim-ulus and DNA repair was found to be the most enriche ional validation analysis of these genes highlighted GINS2 a ccu-mulation of endogenous DNA damage, and impairing and induction of polyploidy by suppression of GINS2 was atic analysis of published gene expression and DNA copy NS2 to be associated with the aggressive characteristics o lear GINS2 protein levels distinguished actively proliferating g as tial t Abbreviati qRT- ll spot microarray
author2 The Pennsylvania State University CiteSeerX Archives
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url http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.252
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf
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geographic Aaltola
Moen
Vollan
geographic_facet Aaltola
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Vollan
genre sami
genre_facet sami
op_source http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf
op_relation http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.688.252
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981730/pdf/neo1211_0877.pdf
op_rights Metadata may be used without restrictions as long as the oai identifier remains attached to it.
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