viral gastroenteritis due to a contaminated well. International consequences. Jama

• Main Authors: Michael Beller, Mph Andrea Ellis, Msc Spencer, H. Lee, Phd Michael, A. Drebot, Sue Anne Jenkerson, Otto D. Simmons Iii, Msph Stephan, S. Monroe, Phd Tamie Ando, Phd Jacqueline Noel
• Other Authors: The Pennsylvania State University CiteSeerX Archives
• Format: Text
• Language: English
• Published: 1997
• Subjects: SMALL ROUND-structured vi; Canada; Jama; Yukon; Alaska
• Online Access: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.476.8739; http://www.unc.edu/courses/2010spring/envr/421/001/readings/noroviruswater.pdf

Context.\p=m-\Small round-structured viruses (SRSVs) are known to cause viral gastroenteritis, but until now have not been confirmed in the implicated vehicle in outbreaks. Objective.\p=m-\Investigation of a gastroenteritis outbreak. Design.\p=m-\After applying epidemiologic methods to locate the outbreak source, we conducted environmental and laboratory investigations to elucidate the cause. Setting.\p=m-\Tourists traveling by bus through Alaska and the Yukon Territory of Canada. Participants.\p=m-\Staff of a restaurant at a business complex implicated as the outbreak source, convenience sample of persons on buses that had stopped there, and bus employees. Main Outcome Measures.\p=m-\Odds ratios (ORs) for illness associated with ex-posures. Water samples from the restaurant and stool specimens from tourists and restaurant staff were examined by nucleic acid amplification using reverse transcription polymerase chain reaction and sequencing of viral amplification prod-