Chemistry Central Journal Poster presentation Molecular modeling studies of lipase-catalyzed β-lactam polymerization
© 2009 Baum et al; licensee BioMed Central Ltd. Enzymatic polymerization has emerged over the last 5 years as a field of considerable interest and commercial promise. The reaction proceeds with high regio-, enantio-, and chemoselectivity under relatively mild conditions. Enzymes have been used so fa...
| Main Authors: | , , , |
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| Format: | Text |
| Language: | English |
| Published: |
2009
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| Subjects: | |
| Online Access: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.429.7053 http://journal.chemistrycentral.com/content/pdf/1752-153X-3-S1-P57.pdf |
| Summary: | © 2009 Baum et al; licensee BioMed Central Ltd. Enzymatic polymerization has emerged over the last 5 years as a field of considerable interest and commercial promise. The reaction proceeds with high regio-, enantio-, and chemoselectivity under relatively mild conditions. Enzymes have been used so far to synthesize polyesters, polysaccharides, polycarbonates, polyphenols, polyanilines, vinyl polymers, and poly-amino acids [1]. Particularly, lipase B of Candida antarctica immobilized on polyacrylic resin (Novozyme 435) has proven to be a very versatile catalyst and has successfully been used for the synthesis of polyesters from various substrates [2][3][4]. Little, however, has been reported on the enzyme catalyzed synthesis of polyamides [5]. While it has been shown that nylons can chemically be produced from the corresponding amino acids or by anionic |
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