Bas.J.Vet.Res.Vol.12,No.1,2013. THE EFFECT OF BISMUTH CHLORIDE ON SOME BLOOD AND BIOCHEMICAL PARAMETERS IN MALE LABORATORY RATS (RATTUS-RATTUS)

The present study amid to characterized the potential toxic effects of bismuth chloride through oral administration on blood and biochiemical parameters of laboratory rats.Solutions of bismuth chloride were chronically feed by stomach tube to rats in(2.5mg/kg and 5 mg/kg).Animals were anesthetized a...

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Bibliographic Details
Main Authors: Zainab A. Shehab, Assad Hassan, Essa Adel, Mousa Hassan
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Subjects:
bismuth
rats
blood parameters
Rattus rattus
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.403.7170
http://www.basjvet.com/wp-content/uploads/2013/04/THE-EFFECT-OF-BISMUTH-CHLORIDE-ON-SOME-BLOOD-AND-BIOCHEMICAL-PARAMETERS-IN-MALE-LABORATORY-RATS.pdf
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Summary:The present study amid to characterized the potential toxic effects of bismuth chloride through oral administration on blood and biochiemical parameters of laboratory rats.Solutions of bismuth chloride were chronically feed by stomach tube to rats in(2.5mg/kg and 5 mg/kg).Animals were anesthetized after two months and blood samples were obtained,blood and biochemical parameters were appreciated between control and experimental Groups.The investigation of blood parameters included red blood cells count (RBC) hemoglobin concentration,packed cell volume PCV and total white blood cell count(WBC)biochemical parameters included total serum cholesterol(TSCH),alanin aminotransferase (ALT) and aspartate aminotransferase(AST).The results showed significant decrease (p≤0.05) of R.B.C count,Hb concentrations PCV value and total W.B.C count in contrast,there was significant increase(p≤0.05) of the total serum cholesterol(,ALTand AST) activities.

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