Dispatches Genetic Evidence of Dobrava Virus in Apodemus agrarius in Hungary

Using nested polymerase chain reaction, we sequenced Dobrava virus (DOB) from the rodent Apodemus agrarius in Hungary. The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching. Hantaviruses, the causative agents of hemorrhagic...

Full description

Bibliographic Details
Main Authors: Jerrold J. Scharninghausen, Hermann Meyer, Martin Pfeffer, Donald S. Davis, Rodney L. Honeycutt
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Subjects:
Europe
Rattus norvegicus
Seoul virus
Clethrionomys glareolus
Puumala virus (PUU
Apodemus flavicollis
Dobrava virus (DOB
and Microtus arvalis
Tula virus (TUL) (3). An
Tula
Microtus arvalis
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.392.1440
http://wwwnc.cdc.gov/eid/article/5/3/pdfs/99-0324.pdf
Description
Summary:Using nested polymerase chain reaction, we sequenced Dobrava virus (DOB) from the rodent Apodemus agrarius in Hungary. The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching. Hantaviruses, the causative agents of hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome, are serologically related viruses of the family Bunyaviridae and have a worldwide distribution. Unlike other bunyaviruses, hantaviruses are not transmitted by arthropod vectors. The virus is excreted in the saliva, urine, and feces of infected rodents. Humans become infected by inhalation of aerosols of dried excreta, inoculation through the conjunctiva, or entry through broken skin (1). Each viral species within the genus Hantavirus is primarily associated with a single rodent species, although accidental infections have been reported in other mammals (2). Four primary reservoirs for hantaviruses are found in

Similar Items