Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa

Abstract: 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All...

Full description

Bibliographic Details
Main Authors: Christoph Timm, Thorsten Mordhorst, Matthias Köck
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Published: 2010
Subjects:
3-alkyl pyridinium alkaloids
Haliclona viscosa
synthesis
marine natural
Arctic
Norway
Spitsbergen
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.355.530
Description
Summary:Abstract: 3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity.

Similar Items