Characterization of phocid herpesvirus-1 and-2 as putative alpha- and gammaherpesviruses of North American and European pinnipeds

To study the relationships between herpesviruses recently isolated from different pinniped species, antigenic and genetic analyses were performed. First, herpesviruses isolated from North American harbour seals (Phoca vitulina), a Californian sea lion (Zalophus californianus) and a European grey sea...

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Bibliographic Details
Main Authors: T. C. Harder, M. Harder, H. Vos, K. Kulonen, S. Kennedy-stoskopf, B. Liess, A. D. M. E. Osterhaus
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Subjects:
Eia
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.7663
http://vir.sgmjournals.org/content/77/1/27.full.pdf
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Summary:To study the relationships between herpesviruses recently isolated from different pinniped species, antigenic and genetic analyses were performed. First, herpesviruses isolated from North American harbour seals (Phoca vitulina), a Californian sea lion (Zalophus californianus) and a European grey seal (Halichoerus grypus) were examined in an enzyme immunoassay (EIA) with a panel of monoclonal antibodies which had previously been shown to allow typing of herpesviruses from European harbour seals into two distinct virus types: phocid herpesvirus type-1 and type-2 (PhHV-1 and PhHV-2). The EIA data showed that all but one of the isolates from seals ranging in United States coastal waters were PhHV-2-1ike while the European grey seal herpesvirus was PhHV-l-like. Genetic characterization