EPSTEIN-BARR VIRUS IN NASOPHARYNGEAL AND SALIVARY GLAND CARCINOMAS OF GREENLAND ESKIMOES

Summary.-Biopsy specimens from nasopharyngeal carcinomas (NPC) or salivarygland carcinomas (SGC) in Greenland Eskimoes were examined for the presence of Epstein-Barr virus (EBV) DNA and sera from the patients were tested for EBVspecific antibody titres. Six out of 7 NPCs and one from an undifferenti...

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Bibliographic Details
Main Authors: A. K. Saemundsena, H. Albeckb, J. P. H. Hansenc, N. H. Nielsend, M. Anvrete, W. Henlef, G. Henlef, K. A. Thomsenb, H. K. Kristensenb, G. Kleina
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Published: 1982
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Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.2374
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Summary:Summary.-Biopsy specimens from nasopharyngeal carcinomas (NPC) or salivarygland carcinomas (SGC) in Greenland Eskimoes were examined for the presence of Epstein-Barr virus (EBV) DNA and sera from the patients were tested for EBVspecific antibody titres. Six out of 7 NPCs and one from an undifferentiated SGC were positive for EBV DNA. The EBV-specific antibody spectra and titres of the patients with NPC or undifferentiated SGC conformed to the results of earlier studies in other high-incidence areas. THE EPSTEIN-BARR VIRUS (EBV) was originally detected in cultured African Burkitt's lymphoma (BL) cells in 1964 (Epstein et al., 1964, 1965). Two years later tests for EBV-specific precipitating antibodies suggested an association of the virus with nasopharyngeal carcinoma (NPC) in East African and American