Research Impact of PCB and p,p´-DDE Contaminants on Human Sperm Y:X Chromosome Ratio: Studies in Three European Populations and the Inuit Population in Greenland

OBJECTIVE: Recent studies indicate that persistent organohalogen pollutants (POPs) may contribute to sex ratio changes in offspring of exposed populations. Our aim in the present study was to investigate whether exposure to 2,2´,4,4´,5,5´-hexachlorobiphenyl (PCB-153) and dichlorodiphenyldichloroethe...

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Bibliographic Details
Main Authors: Tarmo Tiido, Anna Rignell-hydbom, Bo A. G. Jönsson, Yvonne Lundberg Giwercman, Henning S. Pedersen, Bogdan Wojtyniak, Jan K. Ludwicki, Vladimir Lesovoy, Valentyna Zvyezday, Marcello Spano, Lars Ryl, Lars Hagmar, Er Giwercman
Other Authors: The Pennsylvania State University CiteSeerX Archives
Format: Text
Language:English
Subjects:
Greenland
inuit
Online Access:http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.9884
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Summary:OBJECTIVE: Recent studies indicate that persistent organohalogen pollutants (POPs) may contribute to sex ratio changes in offspring of exposed populations. Our aim in the present study was to investigate whether exposure to 2,2´,4,4´,5,5´-hexachlorobiphenyl (PCB-153) and dichlorodiphenyldichloroethene (p,p´-DDE) affects sperm Y:X chromosome distribution. SUBJECTS AND METHODS: We obtained semen and blood for analysis of PCB-153 and p,p´-DDE

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