Overexpression of T-bet, GATA-3 and TGF-ss Induces IFN-gamma, IL-4/13A, and IL-17A Expression in Atlantic Salmon

• Published in: Biology
• Main Authors: Slettjord, Tiril H., Sekkenes, Hege J., Chi, Heng, Bogwald, Jarl, Swain, Trilochan, Dalmo, Roy A., Swain, Jaya Kumari
• Format: Report
• Language: English
• Published: MDPI 2020
• Subjects: overexpression; T-bet; GATA-3; TGF-ss; Atlantic salmon; gene expression; Life Sciences & Biomedicine - Other Topics; Biology; Gata
• Online Access: http://ir.qdio.ac.cn/handle/337002/167436; http://ir.qdio.ac.cn/handle/337002/167437; https://doi.org/10.3390/biology9040082

The overexpression of GATA-3, T-bet and TGF-ss may theoretically induce IL-4/A, IFN-gamma and IL-17A expression, respectively. Whether this also applies to fish is not yet known. The plasmid vectors encoding reporter gene (RFP)-tagged T-bet, GATA-3 and TGF-ss were used as overexpression tools, trans...