West Nile Virus Infection in Killer Whale, Texas, USA, 2007

In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WN...

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Bibliographic Details
Other Authors: St. Leger, Judy, Wu, Guang, Anderson, Mark, Dalton, Les, Nilson, Erika, Wang, David
Language:unknown
Subjects:
Dispatch
West Nile virus
killer whale
Orcinus orca
cetaceans
nonsuppurative encephalitis
zoonoses
arboviruses
viruses
Animals
Antigens
Viral
Brain
Encephalitis
Fatal Outcome
Immunohistochemistry
Male
Oligonucleotide Array Sequence Analysis
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis
DNA
Texas
West Nile Fever
Whale
Killer
Killer Whale
Orca
Killer whale
Online Access:http://stacks.cdc.gov/view/cdc/24211/
Description
Summary:In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans. U01 AI070374/AI/NIAID NIH HHS/United States

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