Primary Multidrug-Resistant Mycobacterium tuberculosis in 2 Regions, Eastern Siberia, Russian Federation

Of 235 Mycobacterium tuberculosis isolates from patients who had not received tuberculosis treatment in the Irkutsk oblast and the Sakha Republic (Yakutia), eastern Siberia, 61 (26%) were multidrug resistant. A novel strain, S 256, clustered among these isolates and carried eis-related kanamycin res...

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Bibliographic Details
Other Authors: Zhdanova, Svetlana, Heysell, Scott K., Ogarkov, Oleg, Boyarinova, Galina, Alexeeva, Galina, Pholwat, Suporn, Zorkaltseva, Elena, Houpt, Eric R., Savilov, Eugeniy
Language:unknown
Subjects:
Dispatch
tuberculosis
multidrug-resistant tuberculosis
MDR TB
HIV
Siberia
Russian Federation
genotype
mycobacterial interspersed repetitive unit
MIRU-VNTR
pncA
pyrazinamide
tuberculosis and other mycobacteria
Sakha
Sakha Republic
Yakutia
Online Access:http://stacks.cdc.gov/view/cdc/20917/
Description
Summary:Of 235 Mycobacterium tuberculosis isolates from patients who had not received tuberculosis treatment in the Irkutsk oblast and the Sakha Republic (Yakutia), eastern Siberia, 61 (26%) were multidrug resistant. A novel strain, S 256, clustered among these isolates and carried eis-related kanamycin resistance, indicating a need for locally informed diagnosis and treatment strategies.

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