Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptom...

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Bibliographic Details
Other Authors: Kalthoff, Donata, Breithaupt, Angele, Teifke, Jens P., Globig, Anja, Harder, Timm, Mettenleiter, Thomas C., Beer, Martin
Language:unknown
Subjects:
Eye
RNA
Online Access:http://stacks.cdc.gov/view/cdc/17191/
Description
Summary:Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.