Mutations in Influenza A Virus (H5N1) and Possible Limited Spread, Turkey, 2006

We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died.

Bibliographic Details
Other Authors: Altiok, Ender, Taylan, Fulya, Yenen, Osman Ş., Demirkeser, Gülşah, Bozaci, Mürvet, Önel, Derya, Akcadag, Birsen, Iyisan, A. Selma, Ciblak, Meral, Bozkaya, Emel, Yuksel, Sirin, Badur, Selim
Language:unknown
Subjects:
Dispatch
Avian flu pandemic
H5N1
pandemic
mutation
outbreak
Turkey
Amino Acid Sequence
Animals
Chickens
Disease Outbreaks
Humans
Influenza A Virus
H5N1 Subtype
Influenza in Birds
Influenza
Human
Avian flu
Online Access:http://stacks.cdc.gov/view/cdc/16562/
Description
Summary:We report mutations in influenza A virus (H5N1) strains associated with 2 outbreaks in Turkey. Four novel amino acid changes (Q447L, N556K, and R46K in RNA polymerase and S133A in hemagglutinin) were detected in virus isolates from 2 siblings who died.

Similar Items