Improvement in the efficiency of oxidative phosphorylation in the freshwater eel acclimated to 10.1 MPa hydrostatic pressure.

• Main Authors: Theron, Michael, Guerrero, François, Sebert, Philippe
• Other Authors: Optimisation des régulations physiologiques (ORPHY (EA 4324)), Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2000
• Subjects: fish; pressure; mitochondrial respiration; enzyme activity; energy metabolism; eel; Anguilla anguilla; [SDV]Life Sciences [q-bio]
• Online Access: https://hal.univ-brest.fr/hal-04350995; https://hal.univ-brest.fr/hal-04350995/document; https://hal.univ-brest.fr/hal-04350995/file/jexbio_203_19_3019.pdf

Previous studies have suggested that the efficiency of oxidative phosphorylation in the freshwater eel (Anguilla anguilla) is increased after acclimation to high hydrostatic pressure. Analysis at atmospheric pressure of the respiratory chain complexes showed that, after 21 days at 10.1 MPa, the activity of complex II was decreased to approximately 50% (P<0.01) of the control value and that cytochrome c oxidase (complex IV) activity was significantly increased to 149 % of the control value (P<0.05). ADP/O ratios calculated from mitochondrial respiration measurements were significantly increasedafter acclimation to high hydrostatic pressure (2.87 versus 2.52, P<0.001) when measured in the presence of pyruvate plus malate at atmospheric pressure. These results clearly show an increased oxidative phosphorylation efficiency in response to high-pressure acclimation.