Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo
International audience This study aims to introduce a high internal phase Pickering emulsion (HIPPE) stabilized by bamboo fungus protein gel particles (BGPs), incorporating Antarctic krill oil (KO), as a new delivery formulation to enrich the application of KO. The appropriate proportion of KO (2:8)...
Published in: | Journal of Functional Foods |
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Format: | Article in Journal/Newspaper |
Language: | English |
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HAL CCSD
2022
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Online Access: | https://hal.science/hal-03685322 https://hal.science/hal-03685322/document https://hal.science/hal-03685322/file/1-s2.0-S1756464622002043-main.pdf https://doi.org/10.1016/j.jff.2022.105134 |
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ftccsdartic:oai:HAL:hal-03685322v1 2024-02-27T08:35:24+00:00 Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo Zhang, Minghao Zhu, Jinrui Zhou, Li Kan, Jianquan Zhao, Minjie Huang, Rong Liu, Jikai Marchioni, Eric South-Central MinZu University (SCUEC) Southwest University Chongqing Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires (DSA-IPHC) Institut Pluridisciplinaire Hubert Curien (IPHC) Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS) 2022 https://hal.science/hal-03685322 https://hal.science/hal-03685322/document https://hal.science/hal-03685322/file/1-s2.0-S1756464622002043-main.pdf https://doi.org/10.1016/j.jff.2022.105134 en eng HAL CCSD Elsevier info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jff.2022.105134 hal-03685322 https://hal.science/hal-03685322 https://hal.science/hal-03685322/document https://hal.science/hal-03685322/file/1-s2.0-S1756464622002043-main.pdf doi:10.1016/j.jff.2022.105134 info:eu-repo/semantics/OpenAccess ISSN: 1756-4646 EISSN: 1756-4646 Journal of Functional Foods https://hal.science/hal-03685322 Journal of Functional Foods, 2022, 94, pp.105134. ⟨10.1016/j.jff.2022.105134⟩ Fungus Delivery system Preparation Pickering stabilizer Anti-inflammatory Ulcerative colitis [SDV.IDA]Life Sciences [q-bio]/Food engineering [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy info:eu-repo/semantics/article Journal articles 2022 ftccsdartic https://doi.org/10.1016/j.jff.2022.105134 2024-01-28T01:20:35Z International audience This study aims to introduce a high internal phase Pickering emulsion (HIPPE) stabilized by bamboo fungus protein gel particles (BGPs), incorporating Antarctic krill oil (KO), as a new delivery formulation to enrich the application of KO. The appropriate proportion of KO (2:8) contributed to HIPPE stabilization (φ = 80%). At pH 11, strong electrostatic interaction tended to produce KO-HIPPE with small droplet and homogeneous size (1.5 μm). BGPs dosage either under (0.5%) or high (2.0%) was prone to the destabilization of KO-HIPPE. In vitro studies indicated that KO-HIPPE had no effect on cell viability and suggested the safety and anti-inflammatory effect. In vivo studies showed that KO-HIPPE treatment could improve the clinical symptoms, suppress the overexpression of the pro-inflammatory cytokines (TNF-α and IL-6) and protect the intestinal barrier with function. The findings demonstrated that the HIPPE stabilized on BGPs had excellent loading efficiency of KO and good security, stability and functional activity. Article in Journal/Newspaper Antarc* Antarctic Antarctic Krill Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) Antarctic Journal of Functional Foods 94 105134 |
institution |
Open Polar |
collection |
Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe) |
op_collection_id |
ftccsdartic |
language |
English |
topic |
Fungus Delivery system Preparation Pickering stabilizer Anti-inflammatory Ulcerative colitis [SDV.IDA]Life Sciences [q-bio]/Food engineering [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy |
spellingShingle |
Fungus Delivery system Preparation Pickering stabilizer Anti-inflammatory Ulcerative colitis [SDV.IDA]Life Sciences [q-bio]/Food engineering [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy Zhang, Minghao Zhu, Jinrui Zhou, Li Kan, Jianquan Zhao, Minjie Huang, Rong Liu, Jikai Marchioni, Eric Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
topic_facet |
Fungus Delivery system Preparation Pickering stabilizer Anti-inflammatory Ulcerative colitis [SDV.IDA]Life Sciences [q-bio]/Food engineering [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy |
description |
International audience This study aims to introduce a high internal phase Pickering emulsion (HIPPE) stabilized by bamboo fungus protein gel particles (BGPs), incorporating Antarctic krill oil (KO), as a new delivery formulation to enrich the application of KO. The appropriate proportion of KO (2:8) contributed to HIPPE stabilization (φ = 80%). At pH 11, strong electrostatic interaction tended to produce KO-HIPPE with small droplet and homogeneous size (1.5 μm). BGPs dosage either under (0.5%) or high (2.0%) was prone to the destabilization of KO-HIPPE. In vitro studies indicated that KO-HIPPE had no effect on cell viability and suggested the safety and anti-inflammatory effect. In vivo studies showed that KO-HIPPE treatment could improve the clinical symptoms, suppress the overexpression of the pro-inflammatory cytokines (TNF-α and IL-6) and protect the intestinal barrier with function. The findings demonstrated that the HIPPE stabilized on BGPs had excellent loading efficiency of KO and good security, stability and functional activity. |
author2 |
South-Central MinZu University (SCUEC) Southwest University Chongqing Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires (DSA-IPHC) Institut Pluridisciplinaire Hubert Curien (IPHC) Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS) |
format |
Article in Journal/Newspaper |
author |
Zhang, Minghao Zhu, Jinrui Zhou, Li Kan, Jianquan Zhao, Minjie Huang, Rong Liu, Jikai Marchioni, Eric |
author_facet |
Zhang, Minghao Zhu, Jinrui Zhou, Li Kan, Jianquan Zhao, Minjie Huang, Rong Liu, Jikai Marchioni, Eric |
author_sort |
Zhang, Minghao |
title |
Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
title_short |
Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
title_full |
Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
title_fullStr |
Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
title_full_unstemmed |
Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
title_sort |
antarctic krill oil high internal phase pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo |
publisher |
HAL CCSD |
publishDate |
2022 |
url |
https://hal.science/hal-03685322 https://hal.science/hal-03685322/document https://hal.science/hal-03685322/file/1-s2.0-S1756464622002043-main.pdf https://doi.org/10.1016/j.jff.2022.105134 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctic Krill |
genre_facet |
Antarc* Antarctic Antarctic Krill |
op_source |
ISSN: 1756-4646 EISSN: 1756-4646 Journal of Functional Foods https://hal.science/hal-03685322 Journal of Functional Foods, 2022, 94, pp.105134. ⟨10.1016/j.jff.2022.105134⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jff.2022.105134 hal-03685322 https://hal.science/hal-03685322 https://hal.science/hal-03685322/document https://hal.science/hal-03685322/file/1-s2.0-S1756464622002043-main.pdf doi:10.1016/j.jff.2022.105134 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1016/j.jff.2022.105134 |
container_title |
Journal of Functional Foods |
container_volume |
94 |
container_start_page |
105134 |
_version_ |
1792041955964747776 |