To live with normal GFR: when higher is not better

International audience Eriksen et al. unmask an independent link between a high glomerular filtration rate (GFR) and subclinical cardiovascular damage in a large cohort of nondiabetic middle-aged people in Tromso, Norway. Although others have previously reported an association between estimated GFR...

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Bibliographic Details
Published in:Kidney International
Main Authors: Rognant, Nicolas, Laville, Maurice
Other Authors: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2014
Subjects:
[SDV]Life Sciences [q-bio]
Norway
Tromso
Online Access:https://hal.archives-ouvertes.fr/hal-01859542
https://doi.org/10.1038/ki.2013.545
Description
Summary:International audience Eriksen et al. unmask an independent link between a high glomerular filtration rate (GFR) and subclinical cardiovascular damage in a large cohort of nondiabetic middle-aged people in Tromso, Norway. Although others have previously reported an association between estimated GFR and cardiovascular risk factors, the present work is remarkable in that it relies on measured GFR, thus overcoming potential bias of the limited accuracy of common GFR estimates in individuals with high GFR values.

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