Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers

Immobilized lipase B from Candida antarctica (N435) was investigated as a potential biocatalyst to generate silicone-based chiral polymers from monomers derived from the enzymatic dihydroxylation of bromobenzene. Several conditions and parameters have been investigated for this purpose and lipase tr...

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Bibliographic Details
Main Author: Naoum, Ravi
Other Authors: Centre for Biotechnology
Format: Thesis
Language:English
Published: Brock University 2015
Subjects:
Biocatalysis
Chiral polymers
Silicones
N435
Toluene dioxygenase
Antarc*
Antarctica
Online Access:http://hdl.handle.net/10464/5984
id ftbrockuniv:oai:dr.library.brocku.ca:10464/5984
record_format openpolar
spelling ftbrockuniv:oai:dr.library.brocku.ca:10464/5984 2023-07-16T03:54:26+02:00 Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers Naoum, Ravi Centre for Biotechnology 2015-01-21T15:20:15Z http://hdl.handle.net/10464/5984 eng eng Brock University http://hdl.handle.net/10464/5984 Biocatalysis Chiral polymers Silicones N435 Toluene dioxygenase Electronic Thesis or Dissertation 2015 ftbrockuniv 2023-06-27T22:08:36Z Immobilized lipase B from Candida antarctica (N435) was investigated as a potential biocatalyst to generate silicone-based chiral polymers from monomers derived from the enzymatic dihydroxylation of bromobenzene. Several conditions and parameters have been investigated for this purpose and lipase transesterification preference to each of the free secondary alcohols in the chiral monomers was documented. The N435 was challenged with a series of substrates where the free alcohol moieties were systematically protected in order to study the substrate preference(s) for the transesterification reactions. Thesis Antarc* Antarctica Brock University Digital Repository
institution Open Polar
collection Brock University Digital Repository
op_collection_id ftbrockuniv
language English
topic Biocatalysis
Chiral polymers
Silicones
N435
Toluene dioxygenase
spellingShingle Biocatalysis
Chiral polymers
Silicones
N435
Toluene dioxygenase
Naoum, Ravi
Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
topic_facet Biocatalysis
Chiral polymers
Silicones
N435
Toluene dioxygenase
description Immobilized lipase B from Candida antarctica (N435) was investigated as a potential biocatalyst to generate silicone-based chiral polymers from monomers derived from the enzymatic dihydroxylation of bromobenzene. Several conditions and parameters have been investigated for this purpose and lipase transesterification preference to each of the free secondary alcohols in the chiral monomers was documented. The N435 was challenged with a series of substrates where the free alcohol moieties were systematically protected in order to study the substrate preference(s) for the transesterification reactions.
author2 Centre for Biotechnology
format Thesis
author Naoum, Ravi
author_facet Naoum, Ravi
author_sort Naoum, Ravi
title Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
title_short Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
title_full Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
title_fullStr Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
title_full_unstemmed Lipase-Mediated Enzymatic Catalysis For The Synthesis of New Chiral Polymers
title_sort lipase-mediated enzymatic catalysis for the synthesis of new chiral polymers
publisher Brock University
publishDate 2015
url http://hdl.handle.net/10464/5984
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_relation http://hdl.handle.net/10464/5984
_version_ 1771551672043044864

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