Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair

DNA contains all the information a cell needs to grow, divide, differentiate, and survive. It also dictates how and when a cell should die. DNA damage (particularly double strand breaks i.e. DSBs) may lead to cell death and/or disease. To circumvent DNA breaks, cells use various DNA repair mechanism...

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Bibliographic Details
Main Authors: Brown, Taylor, Alder, Dr. Jonathan
Format: Text
Language:unknown
Published: BYU ScholarsArchive 2018
Subjects:
forward genetic screen
novel genes
NHEJ DNA repair
Physiology
Orca
Online Access:https://scholarsarchive.byu.edu/jur/vol2018/iss1/172
https://scholarsarchive.byu.edu/context/jur/article/1374/viewcontent/auto_convert.pdf
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spelling ftbrighamyoung:oai:scholarsarchive.byu.edu:jur-1374 2024-02-27T08:44:18+00:00 Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair Brown, Taylor Alder, Dr. Jonathan 2018-05-10T07:00:00Z application/pdf https://scholarsarchive.byu.edu/jur/vol2018/iss1/172 https://scholarsarchive.byu.edu/context/jur/article/1374/viewcontent/auto_convert.pdf unknown BYU ScholarsArchive https://scholarsarchive.byu.edu/jur/vol2018/iss1/172 https://scholarsarchive.byu.edu/context/jur/article/1374/viewcontent/auto_convert.pdf Journal of Undergraduate Research forward genetic screen novel genes NHEJ DNA repair Physiology text 2018 ftbrighamyoung 2024-01-28T17:50:05Z DNA contains all the information a cell needs to grow, divide, differentiate, and survive. It also dictates how and when a cell should die. DNA damage (particularly double strand breaks i.e. DSBs) may lead to cell death and/or disease. To circumvent DNA breaks, cells use various DNA repair mechanisms including non-homologous end joining (NHEJ). My ORCA research project focused on identifying novel genes involved in NHEJ. I did this by performing a forward genetic screen (FGS) that tested every known gene in the genome for involvement in NHEJ. Text Orca Brigham Young University (BYU): ScholarsArchive
institution Open Polar
collection Brigham Young University (BYU): ScholarsArchive
op_collection_id ftbrighamyoung
language unknown
topic forward genetic screen
novel genes
NHEJ DNA repair
Physiology
spellingShingle forward genetic screen
novel genes
NHEJ DNA repair
Physiology
Brown, Taylor
Alder, Dr. Jonathan
Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
topic_facet forward genetic screen
novel genes
NHEJ DNA repair
Physiology
description DNA contains all the information a cell needs to grow, divide, differentiate, and survive. It also dictates how and when a cell should die. DNA damage (particularly double strand breaks i.e. DSBs) may lead to cell death and/or disease. To circumvent DNA breaks, cells use various DNA repair mechanisms including non-homologous end joining (NHEJ). My ORCA research project focused on identifying novel genes involved in NHEJ. I did this by performing a forward genetic screen (FGS) that tested every known gene in the genome for involvement in NHEJ.
format Text
author Brown, Taylor
Alder, Dr. Jonathan
author_facet Brown, Taylor
Alder, Dr. Jonathan
author_sort Brown, Taylor
title Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
title_short Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
title_full Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
title_fullStr Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
title_full_unstemmed Forward Genetic Screen to Identify Novel Genes Involved in NHEJ DNA Repair
title_sort forward genetic screen to identify novel genes involved in nhej dna repair
publisher BYU ScholarsArchive
publishDate 2018
url https://scholarsarchive.byu.edu/jur/vol2018/iss1/172
https://scholarsarchive.byu.edu/context/jur/article/1374/viewcontent/auto_convert.pdf
genre Orca
genre_facet Orca
op_source Journal of Undergraduate Research
op_relation https://scholarsarchive.byu.edu/jur/vol2018/iss1/172
https://scholarsarchive.byu.edu/context/jur/article/1374/viewcontent/auto_convert.pdf
_version_ 1792052708682760192

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