Systemic lupus erythematosus associated with sickle-cell disease: a case report and literature review

• Main Authors: Maamar, Mouna, Tazi-Mezalek, Zoubida, Harmouche, Hicham, Mounfaloti, Wafaa, Adnaoui, Mohammed, Aouni, Mohammed
• Format: Report
• Language: English
• Published: BioMed Central Ltd. 2012
• Subjects: Sickle-cell disease; systemic lupus erythematosus; Sickle; The Pointers
• Online Access: http://www.jmedicalcasereports.com/content/6/1/366

Abstract Introduction The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease. Case presentation We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. The diagnosis of systemic lupus erythematosus was delayed because our patient’s symptoms were initially attributed to sickle-cell disease. Conclusions Physicians should be alerted to the possible association of sickle-cell disease and systemic lupus erythematosus so as not to delay correct diagnosis and initiation of appropriate treatment.