CO2 induced pHi changes in the brain of polar fish: a TauCEST application
Chemical exchange saturation transfer from taurine to water (TauCEST) is primarily detectable in the low temperature range. Since, TauCEST asymmetry is bijective in the physiological pH-range (6.8-7.5), TauCEST is a potential candidate for in vivo studies on brain of polar fish. The specificity of T...
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ftawi:oai:epic.awi.de:51195 2023-05-15T18:02:03+02:00 CO2 induced pHi changes in the brain of polar fish: a TauCEST application Wermter, Felizitas C. Maus, Bastian Pörtner, Hans-Otto Dreher, Wolfgang Bock, Christian 2018 application/pdf https://epic.awi.de/id/eprint/51195/ https://epic.awi.de/id/eprint/51195/1/Paris.pdf https://hdl.handle.net/10013/epic.8639f652-7b00-461d-be8e-6343266f5877 https://hdl.handle.net/ unknown https://epic.awi.de/id/eprint/51195/1/Paris.pdf https://hdl.handle.net/ Wermter, F. C. , Maus, B. orcid:0000-0003-1872-9097 , Pörtner, H. O. orcid:0000-0001-6535-6575 , Dreher, W. and Bock, C. orcid:0000-0003-0052-3090 (2018) CO2 induced pHi changes in the brain of polar fish: a TauCEST application , Joint Annual Meeting ISMRM-ESMRMB, Paris, France, 16 June 2018 - 21 June 2018 . hdl:10013/epic.8639f652-7b00-461d-be8e-6343266f5877 EPIC3Joint Annual Meeting ISMRM-ESMRMB, Paris, France, 2018-06-16-2018-06-21 Conference notRev 2018 ftawi 2021-12-24T15:45:14Z Chemical exchange saturation transfer from taurine to water (TauCEST) is primarily detectable in the low temperature range. Since, TauCEST asymmetry is bijective in the physiological pH-range (6.8-7.5), TauCEST is a potential candidate for in vivo studies on brain of polar fish. The specificity of TauCEST MRI on the brain of polar cod at 1.5°C shows a taurine contribution of 65%. TauCEST in brain of polar cod significantly increased under elevated CO2 concentrations by about 1.34%-3.17% in comparison to control, reflecting pHi changes since localized 1H NMR spectra show no significant changes in metabolite concentration for the different treatments. Conference Object polar cod Alfred Wegener Institute for Polar- and Marine Research (AWI): ePIC (electronic Publication Information Center) |
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Open Polar |
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Alfred Wegener Institute for Polar- and Marine Research (AWI): ePIC (electronic Publication Information Center) |
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ftawi |
language |
unknown |
description |
Chemical exchange saturation transfer from taurine to water (TauCEST) is primarily detectable in the low temperature range. Since, TauCEST asymmetry is bijective in the physiological pH-range (6.8-7.5), TauCEST is a potential candidate for in vivo studies on brain of polar fish. The specificity of TauCEST MRI on the brain of polar cod at 1.5°C shows a taurine contribution of 65%. TauCEST in brain of polar cod significantly increased under elevated CO2 concentrations by about 1.34%-3.17% in comparison to control, reflecting pHi changes since localized 1H NMR spectra show no significant changes in metabolite concentration for the different treatments. |
format |
Conference Object |
author |
Wermter, Felizitas C. Maus, Bastian Pörtner, Hans-Otto Dreher, Wolfgang Bock, Christian |
spellingShingle |
Wermter, Felizitas C. Maus, Bastian Pörtner, Hans-Otto Dreher, Wolfgang Bock, Christian CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
author_facet |
Wermter, Felizitas C. Maus, Bastian Pörtner, Hans-Otto Dreher, Wolfgang Bock, Christian |
author_sort |
Wermter, Felizitas C. |
title |
CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
title_short |
CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
title_full |
CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
title_fullStr |
CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
title_full_unstemmed |
CO2 induced pHi changes in the brain of polar fish: a TauCEST application |
title_sort |
co2 induced phi changes in the brain of polar fish: a taucest application |
publishDate |
2018 |
url |
https://epic.awi.de/id/eprint/51195/ https://epic.awi.de/id/eprint/51195/1/Paris.pdf https://hdl.handle.net/10013/epic.8639f652-7b00-461d-be8e-6343266f5877 https://hdl.handle.net/ |
genre |
polar cod |
genre_facet |
polar cod |
op_source |
EPIC3Joint Annual Meeting ISMRM-ESMRMB, Paris, France, 2018-06-16-2018-06-21 |
op_relation |
https://epic.awi.de/id/eprint/51195/1/Paris.pdf https://hdl.handle.net/ Wermter, F. C. , Maus, B. orcid:0000-0003-1872-9097 , Pörtner, H. O. orcid:0000-0001-6535-6575 , Dreher, W. and Bock, C. orcid:0000-0003-0052-3090 (2018) CO2 induced pHi changes in the brain of polar fish: a TauCEST application , Joint Annual Meeting ISMRM-ESMRMB, Paris, France, 16 June 2018 - 21 June 2018 . hdl:10013/epic.8639f652-7b00-461d-be8e-6343266f5877 |
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1766171728683204608 |