Association of dairy consumption with metabolic syndrome, hypertension and diabetes in 147 812 individuals from 21 countries

• Published in: BMJ Open Diabetes Research & Care
• Main Authors: Bhavadharini, Balaji, Dehghan, Mahshid, Mente, Andrew, Rangarajan, Sumathy, Sheridan, Patrick, Mohan, Viswanathan, Iqbal, Romaina, Gupta, Rajeev, Lear, Scott, Wentzel-Viljoen, Edelweiss, Avezum, Alvaro, Lopez-Jaramillo, Patricio, Mony, Prem, Varma, Ravi Prasad, Kumar, Rajesh, Chifamba, Jephat, Alhabib, Khalid F., Mohammadifard, Noushin, Oguz, Aytekin, Lanas, Fernando, Rozanska, Dorota, Bengtsson Bostrom, Kristina, Yusoff, Khalid, Tsolkile, Lungiswa P., Dans, Antonio, Yusufali, Afzalhussein, Orlandini, Andres, Poirier, Paul, Khatib, Rasha, Hu, Bo, Wei, Li, Yin, Lu
• Format: Text
• Language: unknown
• Published: Advocate Aurora Health Institutional Repository 2020
• Subjects: adult diabetes; endocrinology; hypertension; nutrition; Advocate Aurora Research Institute; Aurora Research Institute
• Online Access: https://institutionalrepository.aah.org/pop/33; https://doi.org/10.1136/bmjdrc-2019-000826; https://xk8bg6rv9a.search.serialssolutions.com/?ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Association+of+dairy+consumption+with+metabolic+syndrome,+hypertension+and+diabetes+in+147%E2%80%89812+individuals+from+21+countries&rft.jtitle=BMJ+open+diabetes+research+%26+care&rft.au=Bhavadharini,+Balaji&rft.au=Dehghan,+Mahshid&rft.au=Mente,+Andrew&rft.au=Rangarajan,+Sumathy&rft.date=2020-05-18&rft.eissn=2052-4897&rft.volume=8&rft.issue=1&rft_id=info:doi/10.1136%2Fbmjdrc-2019-000826&rft.externalDocID=10_1136_bmjdrc_2019_000826&paramdict=en-US

Objective: Our aims were to assess the association of dairy intake with prevalence of metabolic syndrome (MetS) (cross-sectionally) and with incident hypertension and incident diabetes (prospectively) in a large multinational cohort study. Methods: The Prospective Urban Rural Epidemiology (PURE) study is a prospective epidemiological study of individuals aged 35 and 70 years from 21 countries on five continents, with a median follow-up of 9.1 years. In the cross-sectional analyses, we assessed the association of dairy intake with prevalent MetS and its components among individuals with information on the five MetS components (n=112 922). For the prospective analyses, we examined the association of dairy with incident hypertension (in 57 547 individuals free of hypertension) and diabetes (in 131 481 individuals free of diabetes). Results: In cross-sectional analysis, higher intake of total dairy (at least two servings/day compared with zero intake; OR 0.76, 95% CI 0.71 to 0.80, p-trend Conclusions: Higher intake of whole fat (but not low fat) dairy was associated with a lower prevalence of MetS and most of its component factors, and with a lower incidence of hypertension and diabetes. Our findings should be evaluated in large randomized trials of the effects of whole fat dairy on the risks of MetS, hypertension, and diabetes.