Cushing syndrome: update on testing

Endogenous hypercortisolism (Cushing syndrome) is one of the most enigmatic diseases in clinical medicine. The diagnosis and differential diagnosis of Cushing syndrome depend on proper laboratory evaluation. In this review, an update is provided on selected critical issues in the diagnosis and diffe...

Full description

Bibliographic Details
Published in:Endocrinology and Metabolism Clinics of North America
Main Author: Raff, Hershel
Format: Text
Language:unknown
Published: Advocate Aurora Health Institutional Repository 2015
Subjects:
Adrenal incidentalomas
Cushing disease
Inferior petrosal sinus sampling
Salivary cortisol
Advocate Aurora Research Institute
Aurora Research Institute
Online Access:https://institutionalrepository.aah.org/endo/20
https://doi.org/10.1016/j.ecl.2014.10.005
Description
Summary:Endogenous hypercortisolism (Cushing syndrome) is one of the most enigmatic diseases in clinical medicine. The diagnosis and differential diagnosis of Cushing syndrome depend on proper laboratory evaluation. In this review, an update is provided on selected critical issues in the diagnosis and differential diagnosis of Cushing syndrome: the use of late-night salivary cortisol in initial diagnosis and for postoperative surveillance, and the use of prolactin measurement to improve the performance of inferior petrosal sinus sampling to distinguish Cushing disease from ectopic adrenocorticotropic hormone (ACTH) syndrome during differential diagnosis of ACTH-dependent Cushing syndrome.

Similar Items