Study of a method to prepare novel carbonate-containing apatite porous bodies

• Main Author: 2433-0191
• Format: Report
• Language: English
• Published: 2018
• Subjects: Carbonate-containing apatite; Dibasic calcium phosphate dihydrate; Porous body; Carbonic acid
• Online Access: https://asahi-u.repo.nii.ac.jp/?action=repository_uri&item_id=9795; http://id.nii.ac.jp/1128/00009731/; https://asahi-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=9795&item_no=1&attribute_id=97&file_no=1

Bone apatite contains about 5 to 8% carbonate groups. Sintered carbonate-containing apatite has been proposed as a bone substitute material due to its excellent biocompatibility and bioabsorbability. However, sintering increases crystallization, carbonate ions are lost, and absorbability decreases. Therefore, we examined the transition conditions of carbonate-containing apatite in solution at a temperature close to that of the living body to develop a method to obtain unsintered carbonate-containing apatite. Using dibasic calcium phosphate dihydrate as the starting material, carbonate-containing apatite with continuous pores and more carbonic acid groups than the sintered material could be produced.