Study of a method to prepare novel carbonate-containing apatite porous bodies
Bone apatite contains about 5 to 8% carbonate groups. Sintered carbonate-containing apatite has been proposed as a bone substitute material due to its excellent biocompatibility and bioabsorbability. However, sintering increases crystallization, carbonate ions are lost, and absorbability decreases....
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| Format: | Report |
| Language: | English |
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2018
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| Online Access: | https://asahi-u.repo.nii.ac.jp/?action=repository_uri&item_id=9795 http://id.nii.ac.jp/1128/00009731/ https://asahi-u.repo.nii.ac.jp/?action=repository_action_common_download&item_id=9795&item_no=1&attribute_id=97&file_no=1 |
| Summary: | Bone apatite contains about 5 to 8% carbonate groups. Sintered carbonate-containing apatite has been proposed as a bone substitute material due to its excellent biocompatibility and bioabsorbability. However, sintering increases crystallization, carbonate ions are lost, and absorbability decreases. Therefore, we examined the transition conditions of carbonate-containing apatite in solution at a temperature close to that of the living body to develop a method to obtain unsintered carbonate-containing apatite. Using dibasic calcium phosphate dihydrate as the starting material, carbonate-containing apatite with continuous pores and more carbonic acid groups than the sintered material could be produced. |
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