Lipophilic Toxin Profile in Mytilus galloprovincialis from the North Atlantic Coast of Morocco: LC-MS/MS and Mouse Bioassay Analyses

Forthe Moroccan Phycotoxins Monitoring that is part of theSafety of theCoastal Monitoring Network(RSSL),shellfish sampleswereharvestedfromdifferentlocations at NorthAtlantic of Morocco whereharmful algaeblooms were known to have occurred. Forallshellfishsamples found positive by themouse bioassay fo...

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Bibliographic Details
Main Authors: Ben Haddouch, Asia, Amanhi, Rachid, Amzil, Zouher, Taleb, Hamib, Rovillon, Georges-augustin, Adly, Farida, Loutfi, Mohammed
Format: Article in Journal/Newspaper
Language:English
Published: 2017
Subjects:
diarrheictoxins
lipophilic toxins
LC-MS/MS
mouse test
shellfish
North Atlantic
Online Access:https://archimer.ifremer.fr/doc/00372/48342/48495.pdf
https://doi.org/10.21275/24121602
https://archimer.ifremer.fr/doc/00372/48342/
Description
Summary:Forthe Moroccan Phycotoxins Monitoring that is part of theSafety of theCoastal Monitoring Network(RSSL),shellfish sampleswereharvestedfromdifferentlocations at NorthAtlantic of Morocco whereharmful algaeblooms were known to have occurred. Forallshellfishsamples found positive by themouse bioassay fordiarrheicshellfishpoisoning(DSP)toxins,liquid chromatography coupled to tandem massspectrometry(LC-MS-MS) in order to search thefollowinglipophilictoxins: okadaic acid (OA), dinophysistoxins(DTXs), pectenotoxins(PTXs), azaspiracids(AZAs), yessotoxins(YTXs), spirolides(SPXs) and gymnodimines (GYMs).Theresultsrevealeddifferentlipophilictoxinprofiles as a function of theshellfish sampling location. It has beennoticed that allthesamples contained OA and its derivativesnamed dinophysistoxins(DTXs). In addition, other lipophilictoxinswerefound in shellfishsamples:(YTXs), and pectenotoxins(PTX-2, PTX-2-seco-acid and 7- epi-PTX-2-seco-acid) on theNorthAtlantic coast .This paper reports on thefirstdetection of YTXs,PTXsGYMs and their derivatives in Moroccan shellfish.

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