Chikungunya Virus Transmission Potential by Local Aedes Mosquitoes in the Americas and Europe

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Vega-Rúa, Anubis, Lourenço-De-Oliveira, Ricardo, Mousson, Laurence, Vazeille, Marie, Fuchs, Sappho, Yébakima, André, Gustave, Joel, Girod, Romain, Dusfour, Isabelle, Leparc-Goffart, Isabelle, Vanlandingham, Dana L., Huang, Yan-Jang S., Lounibos, L. Philip, Mohamed Ali, Souand, Nougairede, Antoine, de Lamballerie, Xavier, Failloux, Anna-Bella
• Other Authors: Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie (UPMC), Université Pierre et Marie Curie - Paris 6 (UPMC), Arbovirus et Insectes Vecteurs - Arboviruses and Insect Vectors, Institut Pasteur Paris (IP), Laboratório de Mosquitos Transmissores de Hematozoários Rio de Janeiro, Instituto Oswaldo Cruz = Oswaldo Cruz Institute Rio de Janeiro (IOC), Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Démoustication, Conseil Général de Martinique, Agence régionale de santé (ARS) de Martinique (ARS Martinique), Unité d'entomologie médicale, Vectopôle Amazonien Emile Abonnenc Cayenne, Guyane française, Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur de la Guyane, Centre National de Référence (CNR) des Arbovirus - Laboratoire coordonnateur : Equipe Résidente de Recherche d'Infectiologie Tropicale (ERRIT), Institut de Recherche Biomédicale des Armées Hôpital d’Instruction des Armées Laveran, Department of Diagnostic Medicine and Pathobiology, Kansas State University, Biosecurity Research Institute, Florida Medical Entomology Laboratory (IFAS), Florida Atlantic University Boca Raton, Assistance Publique - Hôpitaux de Marseille (APHM), Emergence des Pathologies Virales (EPV), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2015
• Subjects: PUBLIC-HEALTH; ALBOPICTUS; OUTBREAK; AEGYPTI; ARBOVIRUS; INFECTION; SURVEILLANCE; REEMERGENCE; COMPETENCE; EMERGENCE; [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology; Martin Island
• Online Access: https://amu.hal.science/hal-01213833; https://amu.hal.science/hal-01213833/document; https://amu.hal.science/hal-01213833/file/fetchObject.pdf; https://doi.org/10.1371/journal.pntd.0003780

International audience Background Chikungunya virus (CHIKV), mainly transmitted in urban areas by the mosquitoes Aedes aegypti and Aedes albopictus, constitutes a major public health problem. In late 2013, CHIKV emerged on Saint-Martin Island in the Caribbean and spread throughout the region reaching more than 40 countries. Thus far, Ae. aegypti mosquitoes have been implicated as the sole vector in the outbreaks, leading to the hypothesis that CHIKV spread could be limited only to regions where this mosquito species is dominant. Methodology/Principal Findings We determined the ability of local populations of Ae. aegypti and Ae. albopictus from the Americas and Europe to transmit the CHIKV strain of the Asian genotype isolated from Saint-Martin Island (CHIKV_SM) during the recent epidemic, and an East-Central-South African (ECSA) genotype CHIKV strain isolated from La Reunion Island (CHIKV_LR) as a well-characterized control virus. We also evaluated the effect of temperature on transmission of CHIKV_SM by European Ae. albopictus. We found that (i) Aedes aegypti from Saint-Martin Island transmit CHIKV_SM and CHIKV_LR with similar efficiency, (ii) Ae. aegypti from the Americas display similar transmission efficiency for CHIKV_SM, (iii) American and European populations of the alternative vector species Ae. albopictus were as competent as Ae. aegypti populations with respect to transmission of CHIKV_SM and (iv) exposure of European Ae. albopictus to low temperatures (20 degrees C) significantly reduced the transmission potential for CHIKV_SM. Conclusions/Significance CHIKV strains belonging to the ECSA genotype could also have initiated local transmission in the new world. Additionally, the ongoing CHIKV outbreak in the Americas could potentially spread throughout Ae. aegypti-and Ae. albopictus-infested regions of the Americas with possible imported cases of CHIKV to Ae. albopictus-infested regions in Europe. Colder temperatures may decrease the local transmission of CHIKV_SM by European Ae. albopictus, ...