Controlled Enzymatic Synthesis of Polyesters Based on a Cellulose-Derived Triol Monomer: A Design of Experiment Approach

International audience Abstract Regioselective enzymatic polycondensation of the bio–based cellulose derived polyol, Triol–citro, and dimethyl adipate using Candida antarctica Lipase B (CaLB) was investigated. A Design of Experiment approach with MODDE® Pro 13 was used to determine important factors...

Full description

Bibliographic Details
Published in:ChemSusChem
Main Authors: Warne, Cicely, Fadlallah, Sami, Allais, Florent, Guebitz, Georg, Pellis, Alessandro
Other Authors: Austrian Centre of Industrial Biotechnology GmbH (ACIB), Universität für Bodenkultur Wien = University of Natural Resources and Life Sciences Vienne, Autriche (BOKU), Agro-Biotechnologies Industrielles (ABI), AgroParisTech, Università degli studi di Genova = University of Genoa (UniGe), Grand Reims, Département de la Marne and Grand Est Region, European Project: 953073,UPLIFT
Format: Article in Journal/Newspaper
Language:English
Published: HAL CCSD 2024
Subjects:
Bio-based
Enzyme catalysis
Green Chemistry
NMR spectroscopy
Polyesters References
[CHIM.POLY]Chemical Sciences/Polymers
Antarc*
Antarctica
Online Access:https://agroparistech.hal.science/hal-04652003
https://agroparistech.hal.science/hal-04652003/document
https://agroparistech.hal.science/hal-04652003/file/Warne%20et%20al_ChemSusChem_2024.pdf
https://doi.org/10.1002/cssc.202301841
Description
Summary:International audience Abstract Regioselective enzymatic polycondensation of the bio–based cellulose derived polyol, Triol–citro, and dimethyl adipate using Candida antarctica Lipase B (CaLB) was investigated. A Design of Experiment approach with MODDE® Pro 13 was used to determine important factors in the branching behavior of this polymer, and reactant ratio, temperature, reaction time and enzyme wt % were the studied factors. Multifunctional polyesters with pendant hydroxy groups were synthesized and fully characterized using 2D NMR techniques to determine degree of branching. Branching was minimal, with a maximum of 16 % observed, and monomer ratio, temperature and reaction time were all determined to be significant factors. In this work, M n of up to 13 kDa were achieved, while maintaining degree of branching below 15 %, resulting in a linear polyester with the potential to be further functionalized.

Similar Items