Lipase-Induced Oxidative Furan Rearrangements

Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of...

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Published in:Synlett
Main Authors: Blume, Fabian, Sprengart, Petra, Deska, Jan
Other Authors: Department of Chemistry and Materials Science, University of Cologne, Aalto-yliopisto, Aalto University
Format: Article in Journal/Newspaper
Language:English
Published: 2018
Subjects:
Online Access:https://aaltodoc.aalto.fi/handle/123456789/35290
https://doi.org/10.1055/s-0036-1591889
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spelling ftaaltouniv:oai:aaltodoc.aalto.fi:123456789/35290 2023-05-15T13:34:36+02:00 Lipase-Induced Oxidative Furan Rearrangements Blume, Fabian Sprengart, Petra Deska, Jan Department of Chemistry and Materials Science University of Cologne Aalto-yliopisto Aalto University 2018-01-15 application/pdf https://aaltodoc.aalto.fi/handle/123456789/35290 https://doi.org/10.1055/s-0036-1591889 en eng Synlett Volume 29, issue 10 Blume , F , Sprengart , P & Deska , J 2018 , ' Lipase-Induced Oxidative Furan Rearrangements ' , Synlett , vol. 29 , no. 10 , pp. 1293-1296 . https://doi.org/10.1055/s-0036-1591889 0936-5214 PURE UUID: d730bc57-8d06-46da-b834-fe100e6505a2 PURE ITEMURL: https://research.aalto.fi/en/publications/d730bc57-8d06-46da-b834-fe100e6505a2 PURE LINK: http://www.scopus.com/inward/record.url?scp=85040700068&partnerID=8YFLogxK PURE FILEURL: https://research.aalto.fi/files/30119558/CHEM_Blume_et_al_Lipase_Induced_Oxidative_2018_Synlett.pdf https://aaltodoc.aalto.fi/handle/123456789/35290 URN:NBN:fi:aalto-201812106305 doi:10.1055/s-0036-1591889 openAccess Achmatowicz furan heterocyclic chemistry pyranone ring expansion synthetic methodology A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä 2018 ftaaltouniv https://doi.org/10.1055/s-0036-1591889 2022-12-15T19:18:13Z Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines. Peer reviewed Article in Journal/Newspaper Antarc* Antarctica Aalto University Publication Archive (Aaltodoc) Synlett 29 10 1293 1296
institution Open Polar
collection Aalto University Publication Archive (Aaltodoc)
op_collection_id ftaaltouniv
language English
topic Achmatowicz
furan
heterocyclic chemistry
pyranone
ring expansion
synthetic methodology
spellingShingle Achmatowicz
furan
heterocyclic chemistry
pyranone
ring expansion
synthetic methodology
Blume, Fabian
Sprengart, Petra
Deska, Jan
Lipase-Induced Oxidative Furan Rearrangements
topic_facet Achmatowicz
furan
heterocyclic chemistry
pyranone
ring expansion
synthetic methodology
description Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines. Peer reviewed
author2 Department of Chemistry and Materials Science
University of Cologne
Aalto-yliopisto
Aalto University
format Article in Journal/Newspaper
author Blume, Fabian
Sprengart, Petra
Deska, Jan
author_facet Blume, Fabian
Sprengart, Petra
Deska, Jan
author_sort Blume, Fabian
title Lipase-Induced Oxidative Furan Rearrangements
title_short Lipase-Induced Oxidative Furan Rearrangements
title_full Lipase-Induced Oxidative Furan Rearrangements
title_fullStr Lipase-Induced Oxidative Furan Rearrangements
title_full_unstemmed Lipase-Induced Oxidative Furan Rearrangements
title_sort lipase-induced oxidative furan rearrangements
publishDate 2018
url https://aaltodoc.aalto.fi/handle/123456789/35290
https://doi.org/10.1055/s-0036-1591889
genre Antarc*
Antarctica
genre_facet Antarc*
Antarctica
op_relation Synlett
Volume 29, issue 10
Blume , F , Sprengart , P & Deska , J 2018 , ' Lipase-Induced Oxidative Furan Rearrangements ' , Synlett , vol. 29 , no. 10 , pp. 1293-1296 . https://doi.org/10.1055/s-0036-1591889
0936-5214
PURE UUID: d730bc57-8d06-46da-b834-fe100e6505a2
PURE ITEMURL: https://research.aalto.fi/en/publications/d730bc57-8d06-46da-b834-fe100e6505a2
PURE LINK: http://www.scopus.com/inward/record.url?scp=85040700068&partnerID=8YFLogxK
PURE FILEURL: https://research.aalto.fi/files/30119558/CHEM_Blume_et_al_Lipase_Induced_Oxidative_2018_Synlett.pdf
https://aaltodoc.aalto.fi/handle/123456789/35290
URN:NBN:fi:aalto-201812106305
doi:10.1055/s-0036-1591889
op_rights openAccess
op_doi https://doi.org/10.1055/s-0036-1591889
container_title Synlett
container_volume 29
container_issue 10
container_start_page 1293
op_container_end_page 1296
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