Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection

Canada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incide...

Full description

Bibliographic Details
Published in:Canadian Journal of Infectious Diseases and Medical Microbiology
Main Authors: Le Saux, Nicole, Bettinger, Julie A, Wootton, Susan, Halperin, Scott A, Vaudry, Wendy, Scheifele, David W, Tsang, Raymond
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2009
Subjects:
Online Access:http://dx.doi.org/10.1155/2009/871071
http://downloads.hindawi.com/journals/cjidmm/2009/871071.pdf
https://onlinelibrary.wiley.com/doi/pdf/10.1155/2009/871071
Description
Summary:Canada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incidence. The second most common vaccine‐preventable serogroup in Canada is serogroup Y, the incidence of which has been stable. The availability of a quadrivalent conjugate vaccine against serogroups A, C, Y and W135 focuses attention on serogroup Y disease as it becomes relatively more prominent as a cause of vaccine‐preventable invasive meningococcal disease. This vaccine was licensed in November 2006 but is not routinely used except in Nunavut, New Brunswick and Prince Edward Island. To allow a better understanding of the ‘value added’ by a serogroup Y‐containing vaccine, it is necessary to have a contemporary profile of Y disease in Canada. In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized.