Gastric Acid Secretion in a Teleostean Fish A Method for the Continuous Collection of Gastric Effluence from a Swimming Fish and its Response to Histamine and Pentagastrin

Abstract Gastric acid secretion has been measured in the codfish ( Gadus morhua ) equipped with a catheter draining the stomach, by titrating the water swallowed by the fish. Unstimulated acid secretion was found to be very low; in most fishes not exceeding 8 μmol H + /kg.h. Intramuscular injection...

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Bibliographic Details
Published in:Acta Physiologica Scandinavica
Main Author: Holstein, Björn
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1975
Subjects:
Online Access:http://dx.doi.org/10.1111/j.1748-1716.1975.tb10069.x
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Summary:Abstract Gastric acid secretion has been measured in the codfish ( Gadus morhua ) equipped with a catheter draining the stomach, by titrating the water swallowed by the fish. Unstimulated acid secretion was found to be very low; in most fishes not exceeding 8 μmol H + /kg.h. Intramuscular injection of histamine evokes a dose‐dependent secretion of gastric acid, with a maximum acid output of 300 μmol/kg.h occurring with 10 mg/kg histamine dihydrochloride. No acid response was obtained with pentagastrin.