THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS
SUMMARY Twenty‐eight cases of coeliac disease (CD) and seven of dermatitis herpetiformis (DH) have been verified in Iceland. Standard serological techniques were used for HLA typing. Twenty‐five individuals with CD were typed, 21 (84%) of whom carried DR3, DQ2. Twelve of these 25 (48%) had DR3, DR7,...
Published in: | International Journal of Immunogenetics |
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crwiley:10.1111/j.1744-313x.1994.tb00218.x 2023-12-03T10:24:46+01:00 THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS ÁRnason, A. Skaftadóttir, I. Sigmundsson, J. MOONEY, E. Björnsson, J. Cariglia, N. Pálsson, G. Gudjónsson, H. 1994 http://dx.doi.org/10.1111/j.1744-313x.1994.tb00218.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1744-313X.1994.tb00218.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1744-313X.1994.tb00218.x en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor International Journal of Immunogenetics volume 21, issue 6, page 457-460 ISSN 1744-3121 1744-313X Genetics (clinical) Genetics Molecular Biology General Medicine Immunology journal-article 1994 crwiley https://doi.org/10.1111/j.1744-313x.1994.tb00218.x 2023-11-09T13:57:10Z SUMMARY Twenty‐eight cases of coeliac disease (CD) and seven of dermatitis herpetiformis (DH) have been verified in Iceland. Standard serological techniques were used for HLA typing. Twenty‐five individuals with CD were typed, 21 (84%) of whom carried DR3, DQ2. Twelve of these 25 (48%) had DR3, DR7, DQ2, which makes them possibly homozygous for DQ2, and suggests that homozygosity of DQ2 increases the risk for CD. The four DH patients that were typed all had HLA‐B8, DR3, DQ2. It is concluded that CD and DH are associated with DR3, DQZ in Icelanders. Article in Journal/Newspaper Iceland Wiley Online Library (via Crossref) International Journal of Immunogenetics 21 6 457 460 |
institution |
Open Polar |
collection |
Wiley Online Library (via Crossref) |
op_collection_id |
crwiley |
language |
English |
topic |
Genetics (clinical) Genetics Molecular Biology General Medicine Immunology |
spellingShingle |
Genetics (clinical) Genetics Molecular Biology General Medicine Immunology ÁRnason, A. Skaftadóttir, I. Sigmundsson, J. MOONEY, E. Björnsson, J. Cariglia, N. Pálsson, G. Gudjónsson, H. THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
topic_facet |
Genetics (clinical) Genetics Molecular Biology General Medicine Immunology |
description |
SUMMARY Twenty‐eight cases of coeliac disease (CD) and seven of dermatitis herpetiformis (DH) have been verified in Iceland. Standard serological techniques were used for HLA typing. Twenty‐five individuals with CD were typed, 21 (84%) of whom carried DR3, DQ2. Twelve of these 25 (48%) had DR3, DR7, DQ2, which makes them possibly homozygous for DQ2, and suggests that homozygosity of DQ2 increases the risk for CD. The four DH patients that were typed all had HLA‐B8, DR3, DQ2. It is concluded that CD and DH are associated with DR3, DQZ in Icelanders. |
format |
Article in Journal/Newspaper |
author |
ÁRnason, A. Skaftadóttir, I. Sigmundsson, J. MOONEY, E. Björnsson, J. Cariglia, N. Pálsson, G. Gudjónsson, H. |
author_facet |
ÁRnason, A. Skaftadóttir, I. Sigmundsson, J. MOONEY, E. Björnsson, J. Cariglia, N. Pálsson, G. Gudjónsson, H. |
author_sort |
ÁRnason, A. |
title |
THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
title_short |
THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
title_full |
THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
title_fullStr |
THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
title_full_unstemmed |
THE ASSOCIATION BETWEEN COELIAC DISEASE, DERMATITIS HERPETIFORMIS AND CERTAIN HLA‐ANTIGENS IN ICELANDERS |
title_sort |
association between coeliac disease, dermatitis herpetiformis and certain hla‐antigens in icelanders |
publisher |
Wiley |
publishDate |
1994 |
url |
http://dx.doi.org/10.1111/j.1744-313x.1994.tb00218.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1744-313X.1994.tb00218.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1744-313X.1994.tb00218.x |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
International Journal of Immunogenetics volume 21, issue 6, page 457-460 ISSN 1744-3121 1744-313X |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
op_doi |
https://doi.org/10.1111/j.1744-313x.1994.tb00218.x |
container_title |
International Journal of Immunogenetics |
container_volume |
21 |
container_issue |
6 |
container_start_page |
457 |
op_container_end_page |
460 |
_version_ |
1784273326067154944 |