Disseminated intravascular coagulation in farmed Atlantic salmon, Salmo salar L: evidence of consumptive coagulopathy
Abstract. Atlantic salmon, Salmo salar L., suffering from ‘Hitra disease’ showed an increase in activated partial thromboplastin time and prothrombin time values, and a decrease to very low levels of plasma fibrinogen when compared to healthy controls. Together with a marked thrombocytopenia, these...
| Published in: | Journal of Fish Diseases |
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| Main Authors: | , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wiley
1991
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1111/j.1365-2761.1991.tb00600.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2761.1991.tb00600.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2761.1991.tb00600.x |
| Summary: | Abstract. Atlantic salmon, Salmo salar L., suffering from ‘Hitra disease’ showed an increase in activated partial thromboplastin time and prothrombin time values, and a decrease to very low levels of plasma fibrinogen when compared to healthy controls. Together with a marked thrombocytopenia, these results present firm evidence of consumptive coagulopathy with disseminated intravascular coagulation in diseased fish. When the control pen was retested after 4 weeks, a consumptive coagulopathy was evident also in this group of fish. The fact that this pen came down with ‘Hitra disease’ about 8 weeks later strongly supports our hypothesis that DIG is a basic pathologic process in this disease. |
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