A study of variability in the MHC class II β1 and class I α2 domain exons of Atlantic salmon, Salmo salar L.

• Published in: Animal Genetics
• Main Authors: Grimholt, U, Olsaker, I, Lindstrøm, C de Vries, Lie, Ø
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley 1994
• Subjects: Atlantic salmon; Salmo salar
• Online Access: http://dx.doi.org/10.1111/j.1365-2052.1994.tb00103.x; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2052.1994.tb00103.x; https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.1994.tb00103.x

Summary Variability in the most extracellular exons of Atlantic salmon MHC‐Sasa class I and class II was studied by polymerase chain reaction (PCR) amplification followed by sequencing. The domains studied were class I α2 and class II β1. The material used was genomic DNA of fish, mainly derived from the major Norwegian breeding pool, supplemented with some material from a minor breeder and a local river strain. The analysis revealed extensive variation, most individuals being heterozygous with at least two variants.