A study of variability in the MHC class II β1 and class I α2 domain exons of Atlantic salmon, Salmo salar L.

Summary Variability in the most extracellular exons of Atlantic salmon MHC‐Sasa class I and class II was studied by polymerase chain reaction (PCR) amplification followed by sequencing. The domains studied were class I α2 and class II β1. The material used was genomic DNA of fish, mainly derived fro...

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Bibliographic Details
Published in:Animal Genetics
Main Authors: Grimholt, U, Olsaker, I, Lindstrøm, C de Vries, Lie, Ø
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1994
Subjects:
Online Access:http://dx.doi.org/10.1111/j.1365-2052.1994.tb00103.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2052.1994.tb00103.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2052.1994.tb00103.x
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Summary:Summary Variability in the most extracellular exons of Atlantic salmon MHC‐Sasa class I and class II was studied by polymerase chain reaction (PCR) amplification followed by sequencing. The domains studied were class I α2 and class II β1. The material used was genomic DNA of fish, mainly derived from the major Norwegian breeding pool, supplemented with some material from a minor breeder and a local river strain. The analysis revealed extensive variation, most individuals being heterozygous with at least two variants.