Development and characterisation of a novel krill oil nanostructured lipid carrier based on 1,3‐glycerol distearate
Summary A novel nanostructured lipid carrier (NLC) loaded with Antarctic krill oil while using 1,3‐glycerol distearate (GDS) as the solid lipid was prepared through ultrasonication. The NLCs were optimised for ingredient formulation by single‐factor experiment on the basis of their effects on the pa...
| Published in: | International Journal of Food Science & Technology |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wiley
2020
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1111/ijfs.14683 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fijfs.14683 https://onlinelibrary.wiley.com/doi/pdf/10.1111/ijfs.14683 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ijfs.14683 |
| Summary: | Summary A novel nanostructured lipid carrier (NLC) loaded with Antarctic krill oil while using 1,3‐glycerol distearate (GDS) as the solid lipid was prepared through ultrasonication. The NLCs were optimised for ingredient formulation by single‐factor experiment on the basis of their effects on the particle size and polydispersity index (PDI) of the NLCs. 2% (w/w) lecithin and 10% lipid phase of which krill oil accounted for 50% (w/w) were applied to develop the optimised NLC dispersion. The particle size, PDI and zeta potential of this NLC were 112 nm, 0.270 and −30.8 mV, respectively, indicating good dispersion uniformity and stability. Transmission electron microscopy (TEM) revealed that the optimised NLC particles were spherical and uniformly dispersed without apparent aggregation. Differential calorimetry scanning (DSC) and X‐ray diffraction (XRD) showed that the optimised NLC had less‐ordered crystalline structure contributing to the high entrapment efficiency (> 99%) of EPA and DHA. |
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