The effects of mutations, deletions and insertions of single amino acids on the three‐dimensional structure of globins
Using the method of calculation of low energy packings of α‐helices, we studied the effects of mutations, deletions and insertions of amino acids on the structure of sperm whale myoglobin. It was found that these events can cause complete breakdown of this structure.
| Published in: | FEBS Letters |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wiley
1983
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1016/0014-5793(83)80731-5 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2883%2980731-5 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(83)80731-5 https://febs.onlinelibrary.wiley.com/doi/pdf/10.1016/0014-5793%2883%2980731-5 |
| Summary: | Using the method of calculation of low energy packings of α‐helices, we studied the effects of mutations, deletions and insertions of amino acids on the structure of sperm whale myoglobin. It was found that these events can cause complete breakdown of this structure. |
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