Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption
Abstract Oil from the marine copepod, Calanus finmarchicus , which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus ® Oil sup...
Published in: | Lipids |
---|---|
Main Authors: | , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
2016
|
Subjects: | |
Online Access: | http://dx.doi.org/10.1007/s11745-016-4189-y http://link.springer.com/content/pdf/10.1007/s11745-016-4189-y.pdf http://link.springer.com/article/10.1007/s11745-016-4189-y/fulltext.html https://onlinelibrary.wiley.com/doi/full/10.1007/s11745-016-4189-y |
id |
crwiley:10.1007/s11745-016-4189-y |
---|---|
record_format |
openpolar |
spelling |
crwiley:10.1007/s11745-016-4189-y 2024-06-02T08:04:42+00:00 Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption Cook, Chad M. Larsen, Terje S. Derrig, Linda D. Kelly, Kathleen M. Tande, Kurt S. Calanus AS (Tromsø, Norway) 2016 http://dx.doi.org/10.1007/s11745-016-4189-y http://link.springer.com/content/pdf/10.1007/s11745-016-4189-y.pdf http://link.springer.com/article/10.1007/s11745-016-4189-y/fulltext.html https://onlinelibrary.wiley.com/doi/full/10.1007/s11745-016-4189-y en eng Wiley http://onlinelibrary.wiley.com/termsAndConditions#vor http://www.springer.com/tdm Lipids volume 51, issue 10, page 1137-1144 ISSN 0024-4201 1558-9307 journal-article 2016 crwiley https://doi.org/10.1007/s11745-016-4189-y 2024-05-03T11:03:16Z Abstract Oil from the marine copepod, Calanus finmarchicus , which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus ® Oil supplying a total of 260 mg EPA and 156 mg DHA primarily as wax esters, or 1 capsule of Lovaza ® providing 465 mg EPA and 375 mg DHA as ethyl esters, each with an EPA‐ and DHA‐free breakfast. Plasma EPA and DHA were measured over a 72 h period ( t = 1, 2, 4, 6, 8, 10, 12, 24, 48, and 72 h). The positive incremental area under the curve over the 72 h test period (iAUC 0‐72 h ) for both EPA and DHA was significantly different from zero ( p < 0.0001) in both test conditions, with similar findings for the iAUC 0–24 h and iAUC 0–48 h , indicating the fatty acids were absorbed. There was no difference in the plasma iAUC 0–72 h for EPA + DHA, or DHA individually, in response to Calanus Oil vs the ethyl ester condition; however, the iAUC 0–48 h and iAUC 0–72 h for plasma EPA in response to Calanus Oil were both significantly increased relative to the ethyl ester condition (iAUC 0–48 h : 381 ± 31 vs 259 ± 39 μg*h/mL, p = 0.026; iAUC 0‐72 h : 514 ± 47 vs 313 ± 49 μg*h/mL, p = 0.009). These data demonstrate a novel wax ester rich marine oil is a suitable alternative source of EPA and DHA for human consumption. Article in Journal/Newspaper Calanus finmarchicus Wiley Online Library Lipids 51 10 1137 1144 |
institution |
Open Polar |
collection |
Wiley Online Library |
op_collection_id |
crwiley |
language |
English |
description |
Abstract Oil from the marine copepod, Calanus finmarchicus , which contains >86 % of fatty acids present as wax esters, is a novel source of n‐3 fatty acids for human consumption. In a randomized, two‐period crossover study, 18 healthy adults consumed 8 capsules providing 4 g of Calanus ® Oil supplying a total of 260 mg EPA and 156 mg DHA primarily as wax esters, or 1 capsule of Lovaza ® providing 465 mg EPA and 375 mg DHA as ethyl esters, each with an EPA‐ and DHA‐free breakfast. Plasma EPA and DHA were measured over a 72 h period ( t = 1, 2, 4, 6, 8, 10, 12, 24, 48, and 72 h). The positive incremental area under the curve over the 72 h test period (iAUC 0‐72 h ) for both EPA and DHA was significantly different from zero ( p < 0.0001) in both test conditions, with similar findings for the iAUC 0–24 h and iAUC 0–48 h , indicating the fatty acids were absorbed. There was no difference in the plasma iAUC 0–72 h for EPA + DHA, or DHA individually, in response to Calanus Oil vs the ethyl ester condition; however, the iAUC 0–48 h and iAUC 0–72 h for plasma EPA in response to Calanus Oil were both significantly increased relative to the ethyl ester condition (iAUC 0–48 h : 381 ± 31 vs 259 ± 39 μg*h/mL, p = 0.026; iAUC 0‐72 h : 514 ± 47 vs 313 ± 49 μg*h/mL, p = 0.009). These data demonstrate a novel wax ester rich marine oil is a suitable alternative source of EPA and DHA for human consumption. |
author2 |
Calanus AS (Tromsø, Norway) |
format |
Article in Journal/Newspaper |
author |
Cook, Chad M. Larsen, Terje S. Derrig, Linda D. Kelly, Kathleen M. Tande, Kurt S. |
spellingShingle |
Cook, Chad M. Larsen, Terje S. Derrig, Linda D. Kelly, Kathleen M. Tande, Kurt S. Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
author_facet |
Cook, Chad M. Larsen, Terje S. Derrig, Linda D. Kelly, Kathleen M. Tande, Kurt S. |
author_sort |
Cook, Chad M. |
title |
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
title_short |
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
title_full |
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
title_fullStr |
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
title_full_unstemmed |
Wax Ester Rich Oil From The Marine Crustacean, Calanus finmarchicus, is a Bioavailable Source of EPA and DHA for Human Consumption |
title_sort |
wax ester rich oil from the marine crustacean, calanus finmarchicus, is a bioavailable source of epa and dha for human consumption |
publisher |
Wiley |
publishDate |
2016 |
url |
http://dx.doi.org/10.1007/s11745-016-4189-y http://link.springer.com/content/pdf/10.1007/s11745-016-4189-y.pdf http://link.springer.com/article/10.1007/s11745-016-4189-y/fulltext.html https://onlinelibrary.wiley.com/doi/full/10.1007/s11745-016-4189-y |
genre |
Calanus finmarchicus |
genre_facet |
Calanus finmarchicus |
op_source |
Lipids volume 51, issue 10, page 1137-1144 ISSN 0024-4201 1558-9307 |
op_rights |
http://onlinelibrary.wiley.com/termsAndConditions#vor http://www.springer.com/tdm |
op_doi |
https://doi.org/10.1007/s11745-016-4189-y |
container_title |
Lipids |
container_volume |
51 |
container_issue |
10 |
container_start_page |
1137 |
op_container_end_page |
1144 |
_version_ |
1800749353039560704 |