Preparation of millicurie quantities of oxygen‐15 labeled water

Abstract Due to the annihilation radiation of the positron emitting oxygen‐15, H 2 15 O has great potential for tracer studies. The method of preparation utilized the fast exchange reaction between carbon dioxide and carbonic acid. It was found that the rate of exchange depended on the temperature,...

Full description

Bibliographic Details
Published in:Journal of Labelled Compounds
Main Authors: Welch, Michael J., Lifton, Judith F., Ter‐Pogossian, Michel M.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1969
Subjects:
Online Access:http://dx.doi.org/10.1002/jlcr.2590050210
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjlcr.2590050210
https://onlinelibrary.wiley.com/doi/full/10.1002/jlcr.2590050210
Description
Summary:Abstract Due to the annihilation radiation of the positron emitting oxygen‐15, H 2 15 O has great potential for tracer studies. The method of preparation utilized the fast exchange reaction between carbon dioxide and carbonic acid. It was found that the rate of exchange depended on the temperature, the solution used and the dynamic state of the solution. Utilizing this exchange reaction, water with a specific activity of 80 mCi/cc was prepared.