Synthesis and Antifungal Activity of Novel 1,2,4‐Triazole Derivatives Containing 1,2,3‐Thiadiazole Moiety
Starting from carbonic acid diethyl ester, a series of 1,2,4‐triazole derivatives containing 1,2,3‐thiadiazole were synthesized. Reactions were performed by microwave irradiation or ultrasonic irradiation as well as by conventional heating. The structure of title compounds was characterized by 1 H‐N...
| Published in: | Journal of Heterocyclic Chemistry |
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| Main Authors: | , , , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Wiley
2013
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1002/jhet.1656 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjhet.1656 https://onlinelibrary.wiley.com/doi/pdf/10.1002/jhet.1656 |
| Summary: | Starting from carbonic acid diethyl ester, a series of 1,2,4‐triazole derivatives containing 1,2,3‐thiadiazole were synthesized. Reactions were performed by microwave irradiation or ultrasonic irradiation as well as by conventional heating. The structure of title compounds was characterized by 1 H‐NMR, MS, and elemental analyses. The fungicidal activities of these compounds were tested in vivo . Most of title compounds exhibited good antifungal activity against Pseudoperonospora cubensis . Some of title compounds displayed moderate antifungal activities against Fusarium oxysporum , Pseudoperonospora cubensis , Sphaerotheca fuligenea , Corynespora cassiicola , and Xanthomonas axonopodis . |
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