Effect of certain drugs on the incidence of seasickness
Several drugs were tested, some of them for the first time, against seasickness in military personnel on transport ships on the North Atlantic ocean. All of the drugs were given three fimes a day. Of the new ones tested phenglutarmide, 2.5 mg., and cinnarazine, 7.5 mg., were significantly effective...
Published in: | Clinical Pharmacology & Therapeutics |
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Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley
1960
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Subjects: | |
Online Access: | http://dx.doi.org/10.1002/cpt196013280 http://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcpt196013280 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcpt196013280 https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt196013280 |
Summary: | Several drugs were tested, some of them for the first time, against seasickness in military personnel on transport ships on the North Atlantic ocean. All of the drugs were given three fimes a day. Of the new ones tested phenglutarmide, 2.5 mg., and cinnarazine, 7.5 mg., were significantly effective on a single trip. Somewhat less effective were atropine and orphenadrine. Ineffective new drugs were procyclidine, diethazine, cycrimine, caramiphen, pheniprazine, nialamide, phenelzine, benactyzine, and promazine. Cyclizine and meclizine, in doses of 50 mg. three times a day, were again found to be effective. |
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