Distribution of albumin variants Naskapi and Mexico among Aleuts, Frobisher Bay Eskimos, and Micmac, Naskapi, Mohawk, Omaha and Apache Indians

Abstract In order to help define the boundaries of the distribution of the albumin variants Naskapi and Mexico which are polymorphic among several American Indian groups, we examined sera from Micmac, Mohawk, Northwest River Naskapi, Omaha and Apache Indians, and from Aleuts and Eskimos. Sera from a...

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Bibliographic Details
Published in:American Journal of Physical Anthropology
Main Authors: Schell, Lawrence M., Agarwal, Shyam S., Blumberg, Baruch S., Levy, Howard, Bennett, Peter H., Laughlin, William S., Martin, John P.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1978
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Online Access:http://dx.doi.org/10.1002/ajpa.1330490117
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajpa.1330490117
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.1330490117
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Summary:Abstract In order to help define the boundaries of the distribution of the albumin variants Naskapi and Mexico which are polymorphic among several American Indian groups, we examined sera from Micmac, Mohawk, Northwest River Naskapi, Omaha and Apache Indians, and from Aleuts and Eskimos. Sera from a total of 1,524 individuals were examined. Using a cellulose acetate membrane electrophoretic system with Trisā€Citric acid at pH 5.4 we were able to distinguish normal albumin and both variants in the same run. Naskapi and Mexico variants were absent from Aleut, Eskimo, Micmac, Mohawk and Omaha samples. The albumin Naskapi variant was present in an allele frequency of 0.03 in the Naskapi Indian sample. Albumin variants Naskapi and Mexico were found in the Apache sample at frequencies of 0.016 and 0.037, respectively. This report supersedes that previously published by Schell and Agarwal ('76). Generally, within an area there is a correspondence between changes in the frequency of albumin variants and changes in the ethnic background and history of the area's populations. At the same time, when viewing widely separated areas, relationships between distant groups based on linguistic and cultural similarities are paralleled on a biologic level by the distribution of normal albumin and variant albumins.