Stress and the etiology of osteoarthritis

Abstract Although degenerative joint disease is an old and exceedingly common problem, clinical investigators have not reached a consensus regarding the etiology of this disease. Comparative osteological analysis of the knee, hip, shoulder, and elbow joints of 798 individuals from four human skeleta...

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Bibliographic Details
Published in:American Journal of Physical Anthropology
Main Author: Jurmain, Robert D.
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 1977
Subjects:
Online Access:http://dx.doi.org/10.1002/ajpa.1330460214
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fajpa.1330460214
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajpa.1330460214
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Summary:Abstract Although degenerative joint disease is an old and exceedingly common problem, clinical investigators have not reached a consensus regarding the etiology of this disease. Comparative osteological analysis of the knee, hip, shoulder, and elbow joints of 798 individuals from four human skeletal populations (Black and White Americans, Pueblo Indians, and Alaskan Eskimos) indicates that age of onset, frequency, and location of degenerative changes are directly related to the nature and degree of environmentally associated stress, as reflected by the variable life styles of the populations sampled. Eskimos have the earliest onset and most severe involvement for all four joints studied, the right side is usually more affected than the left, and Blacks are more frequently involved than Whites in the knee, shoulder, and elbow. Functional stress, when constant and severe in nature, becomes the primary focus of degenerative disease, but other background contributing agents such as age, sex, and hormonal influence must not be ignored.