Fixation
Fixation is the loss of all but one allele at a particular locus in a population. This may be due to genetic drift (including founder effect and bottleneck) or to selection. The result is a loss of genetic variation in the population. Fixation index (Fst) measures the differentiation of a population...
| Main Author: | |
|---|---|
| Format: | Other/Unknown Material |
| Language: | unknown |
| Published: |
Wiley
2018
|
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1002/9781118584538.ieba0178 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F9781118584538.ieba0178 https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118584538.ieba0178 |
| Summary: | Fixation is the loss of all but one allele at a particular locus in a population. This may be due to genetic drift (including founder effect and bottleneck) or to selection. The result is a loss of genetic variation in the population. Fixation index (Fst) measures the differentiation of a population due to substructure. The Aleut population of Bering Island, Russia is fixed for mitochondrial DNA (mtDNA) haplogroup D. The ancestral Aleut population has both A and D mtDNA types, and fixation of mtDNA D likely resulted from a founder effect associated with historic establishment of the community. |
|---|