The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada
Abstract Objective We previously examined the associations between dietary dichlorodiphenyldichloroethylene (DDE) and polychlorinated biphenyls (PCBs) intake from fish consumption and type 2 diabetes (T2D) prevalence in Ontario and Manitoba. This study aims to further explore the relationship in a r...
Published in: | Canadian Journal of Public Health |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Springer Science and Business Media LLC
2021
|
Subjects: | |
Online Access: | http://dx.doi.org/10.17269/s41997-021-00484-w https://link.springer.com/content/pdf/10.17269/s41997-021-00484-w.pdf https://link.springer.com/article/10.17269/s41997-021-00484-w/fulltext.html |
id |
crspringernat:10.17269/s41997-021-00484-w |
---|---|
record_format |
openpolar |
spelling |
crspringernat:10.17269/s41997-021-00484-w 2023-05-15T16:15:24+02:00 The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada Marushka, Lesya Hu, Xuefeng Batal, Malek Tikhonov, Constantine Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Chan, Hing Man 2021 http://dx.doi.org/10.17269/s41997-021-00484-w https://link.springer.com/content/pdf/10.17269/s41997-021-00484-w.pdf https://link.springer.com/article/10.17269/s41997-021-00484-w/fulltext.html en eng Springer Science and Business Media LLC https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 CC-BY Canadian Journal of Public Health volume 112, issue S1, page 168-182 ISSN 0008-4263 1920-7476 Public Health, Environmental and Occupational Health General Medicine journal-article 2021 crspringernat https://doi.org/10.17269/s41997-021-00484-w 2022-01-04T16:53:06Z Abstract Objective We previously examined the associations between dietary dichlorodiphenyldichloroethylene (DDE) and polychlorinated biphenyls (PCBs) intake from fish consumption and type 2 diabetes (T2D) prevalence in Ontario and Manitoba. This study aims to further explore the relationship in a regionally representative sample of First Nations adults living on-reserve across Canada. Methods Dietary, health and lifestyle data collected by the cross-sectional First Nations Food, Nutrition and Environment Study (2008–2018) were analyzed. This participatory study included 6091 First Nations adult participants who answered questions on T2D. The consumption of locally caught fish was estimated with a food frequency questionnaire. A total of 551 samples from 96 fish species were collected and analyzed for the presence of DDE and PCBs. The associations between fish and dietary DDE/PCBs intake with self-reported T2D were investigated using multiple logistic regression models adjusted for confounders. Results Dietary exposure to DDE (>2.11 ng/kg/bw) and PCBs (>1.47 ng/kg/bw) vs no exposure was positively associated with T2D with ORs of 2.33 (95% CI: 1.24–4.35) for DDE and 1.43 (95% CI: 1.01–3.59) for PCBs. The associations were stronger among females (DDE OR = 3.11 (1.41–6.88); PCBs OR = 1.76 (1.10–3.65)) and older individuals (DDE OR = 2.64 (1.12–6.20); PCBs OR = 1.44 (1.01–3.91)) as compared with males and younger participants. Also, significant dose-response relationships were found for fish consumption in females only. Conclusion This study confirms our previous findings that dietary DDE/PCBs exposure may increase the risk of T2D. The effect of DDE/PCBs from fish consumption is driven by geographical differences in DDE/PCBs concentrations in fish and by the amount of fish consumed, and is more prominent in females than in males. Article in Journal/Newspaper First Nations Springer Nature (via Crossref) Canada Canadian Journal of Public Health 112 S1 168 182 |
institution |
Open Polar |
collection |
Springer Nature (via Crossref) |
op_collection_id |
crspringernat |
language |
English |
topic |
Public Health, Environmental and Occupational Health General Medicine |
spellingShingle |
Public Health, Environmental and Occupational Health General Medicine Marushka, Lesya Hu, Xuefeng Batal, Malek Tikhonov, Constantine Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Chan, Hing Man The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
topic_facet |
Public Health, Environmental and Occupational Health General Medicine |
description |
Abstract Objective We previously examined the associations between dietary dichlorodiphenyldichloroethylene (DDE) and polychlorinated biphenyls (PCBs) intake from fish consumption and type 2 diabetes (T2D) prevalence in Ontario and Manitoba. This study aims to further explore the relationship in a regionally representative sample of First Nations adults living on-reserve across Canada. Methods Dietary, health and lifestyle data collected by the cross-sectional First Nations Food, Nutrition and Environment Study (2008–2018) were analyzed. This participatory study included 6091 First Nations adult participants who answered questions on T2D. The consumption of locally caught fish was estimated with a food frequency questionnaire. A total of 551 samples from 96 fish species were collected and analyzed for the presence of DDE and PCBs. The associations between fish and dietary DDE/PCBs intake with self-reported T2D were investigated using multiple logistic regression models adjusted for confounders. Results Dietary exposure to DDE (>2.11 ng/kg/bw) and PCBs (>1.47 ng/kg/bw) vs no exposure was positively associated with T2D with ORs of 2.33 (95% CI: 1.24–4.35) for DDE and 1.43 (95% CI: 1.01–3.59) for PCBs. The associations were stronger among females (DDE OR = 3.11 (1.41–6.88); PCBs OR = 1.76 (1.10–3.65)) and older individuals (DDE OR = 2.64 (1.12–6.20); PCBs OR = 1.44 (1.01–3.91)) as compared with males and younger participants. Also, significant dose-response relationships were found for fish consumption in females only. Conclusion This study confirms our previous findings that dietary DDE/PCBs exposure may increase the risk of T2D. The effect of DDE/PCBs from fish consumption is driven by geographical differences in DDE/PCBs concentrations in fish and by the amount of fish consumed, and is more prominent in females than in males. |
format |
Article in Journal/Newspaper |
author |
Marushka, Lesya Hu, Xuefeng Batal, Malek Tikhonov, Constantine Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Chan, Hing Man |
author_facet |
Marushka, Lesya Hu, Xuefeng Batal, Malek Tikhonov, Constantine Sadik, Tonio Schwartz, Harold Ing, Amy Fediuk, Karen Chan, Hing Man |
author_sort |
Marushka, Lesya |
title |
The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
title_short |
The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
title_full |
The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
title_fullStr |
The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
title_full_unstemmed |
The relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among First Nations in Canada |
title_sort |
relationship between dietary exposure to persistent organic pollutants from fish consumption and type 2 diabetes among first nations in canada |
publisher |
Springer Science and Business Media LLC |
publishDate |
2021 |
url |
http://dx.doi.org/10.17269/s41997-021-00484-w https://link.springer.com/content/pdf/10.17269/s41997-021-00484-w.pdf https://link.springer.com/article/10.17269/s41997-021-00484-w/fulltext.html |
geographic |
Canada |
geographic_facet |
Canada |
genre |
First Nations |
genre_facet |
First Nations |
op_source |
Canadian Journal of Public Health volume 112, issue S1, page 168-182 ISSN 0008-4263 1920-7476 |
op_rights |
https://creativecommons.org/licenses/by/4.0 https://creativecommons.org/licenses/by/4.0 |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.17269/s41997-021-00484-w |
container_title |
Canadian Journal of Public Health |
container_volume |
112 |
container_issue |
S1 |
container_start_page |
168 |
op_container_end_page |
182 |
_version_ |
1766001133660143616 |