Long term post PrePex male circumcision outcomes in an urban population in Uganda: a cohort study

• Published in: BMC Research Notes
• Main Authors: Galukande, M., Nakaggwa, F., Busisa, E., Sekavuga Bbaale, D., Nagaddya, T., Coutinho, A.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Science and Business Media LLC 2017
• Subjects: General Biochemistry, Genetics and Molecular Biology; General Medicine; Circumcision; SCAR
• Online Access: http://dx.doi.org/10.1186/s13104-017-2845-9; https://link.springer.com/content/pdf/10.1186/s13104-017-2845-9.pdf; https://link.springer.com/article/10.1186/s13104-017-2845-9/fulltext.html

Abstract Objective The objective of this study was to determine the long term adverse events profile at least a year after safe male circumcision. Results A cohort study, investigating patients who had undergone a non surgical circumcision procedure called Prepex. The study variables included scar appearance and sexual experiences. Clients were contacted for a phone interview and data were collected using a questionnaire, for some, a physical examination was done. We obtained ethical committee approval. Data from 304 out of a possible 625 men were analyzed, the rest was lost to follow up. The follow up period was 12–24 months. The mean age was 28 years. Up to 97% were satisfied with the penile scar appearance and the absence of pain. There was no keloids formation, though one developed a hypertrophic scar. Participants reported improved sexual intercourse enjoyment (post circumcision). Up to 17% resumed sexual intercourse before the 6-week long mandatory abstinence period. The average self-reported healing time was 4.7 weeks. There was a high level of scar appearance satisfaction, there was no keloids formation. There was a perceived improvement of sexual enjoyment after circumcision. Trial registration ClinicalTrials. Gov Identifier: NCT02245126 (Date of registration: September 19, 2014)