An account of some experiments on the blood in connexion with the theory of respiration

• Published in: Abstracts of the Papers Printed in the Philosophical Transactions of the Royal Society of London
• Format: Article in Journal/Newspaper
• Language: English
• Published: The Royal Society 1843
• Subjects: Carbonic acid
• Online Access: http://dx.doi.org/10.1098/rspl.1837.0037; https://royalsocietypublishing.org/doi/pdf/10.1098/rspl.1837.0037

The author has investigated, experimentally, several of the important questions connected with the theory of respiration and of animal heat; and arrives at the following results. He finds that the blood is capable of absorbing oxygen both from atmospheric air and from oxygen gas, independently of putrefaction. After blood has been agitated in common air, a trace of carbonic acid not exceeding one per cent., is found in the residual air; but when pure oxygen is employed, no carbonic acid can be detected in it by the most carefully conducted trials. When pure carbonic acid is brought into contact with blood, or serum, over mercury, and moderately agitated, the absorption of gas exceeds the volume of the fluid. Both arterial and venous blood are rendered very dark, and serum more liquid by the absorption of this gas to saturation. Serum, in its healthy state, is incapable of absorbing oxygen, or of immediately furnishing carbon to form carbonic acid: and after it has absorbed carbonic acid, only one-tenth of the absorbed gas is expelled by successive agitation with atmospheric air or with hydrogen. The author is inclined to think that the alkali in the blood, in its healthiest condition, is in the state of a sesquicarbonate. In the majority of trials manifest indications of the disengagement of air from blood in vacuo were obtained: but as it occasionally happened that no air could be thus extricated, the author is induced to believe that the quantity of air contained in the blood is variable: and he has found this air to consist solely of carbonic acid gas. It would also appear, from the experiments detailed in this paper, that a portion of oxygen exists in the blood, not capable of being extracted by the air-pump, yet capable of entering into combination with nitrous gas; and existing in largest proportion in arterial blood. The absorption of oxygen by blood is attended with an increase of temperature. The experiments of the author tend to show that the lungs are absorbing and secreting, and perhaps also inhaling ...